Cavaliers vs. 76ers Prediction: Cleveland to Win, Donovan Mitchell Projected for Big Game in Friday's NBA Matchup [1/24/2025]

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Written by Ryan Leaver

Our expert prediction for Friday's Cleveland Cavaliers vs Philadelphia 76ers matchup.

Cleveland Cavaliers-Philadelphia 76ers Predictions and Game Preview.
Wells Fargo Center sets the stage for the NBA matchup between the Cleveland Cavaliers and Philadelphia 76ers this Friday.

NBA action continues on Friday at 7:00PM ET as the favored Cleveland Cavaliers take on the Philadelphia 76ers at Wells Fargo Center.

The 76ers, with the likes of Tyrese Maxey, Paul George and Kelly Oubre, are set to take on the Cavaliers, whose lineup includes Donovan Mitchell, Darius Garland and Jarrett Allen.

Based on updated simulation results, Dimers' advanced NBA model (see Dimers Pro for full access) predicts the Cavaliers as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Cleveland-Philadelphia game 10,000 times," said Damien Souness from Dimers.

"After computing the latest updates and thousands of other inputs, we predict the Cavaliers' chance of winning is 76%, while the 76ers' is 24%."

For a closer look at Friday's matchup, including the predicted score, best bets and player prop picks, visit our interactive Cavaliers vs. 76ers predictions page.

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Cavs vs. Sixers Game-Day Updates and Essential Details

Friday's action between the 76ers and Cavaliers at Wells Fargo Center is scheduled to begin at 7:00PM ET.

Dimers.com's comprehensive preview of Friday's Cavaliers vs. 76ers matchup includes our prediction, picks and the latest betting odds.

Before making any Cleveland vs. Philadelphia picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

Cavaliers vs. Sixers Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Friday's NBA game between the Cavaliers and 76ers 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Cavaliers a 76% chance of beating the 76ers. Our predicted final score has the Cavaliers winning 119-110.

According to our model, the 76ers (+9.5) have a 54% chance of covering the spread, while the 230.5-point over/under has a 51% chance of staying under.

Pre-Game Probabilities
Last Updated: 12:09AM, Jan 25
Spread
Over / Under
Moneyline
Cavaliers
76ers +9.5
46%
54%
Get the best bets with Dimers Pro
See Matchup
76ers
Cavaliers CLE
76ers +9.5
46%
54%
See Matchup
76ers PHI
Get the best bets with Dimers Pro

Cavaliers vs. 76ers Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type Cavaliers 76ers
Spread -9.5 (-105) +9.5 (-106)
Moneyline -440 +385
Total o230.5 (-105) u230.5 (-112)

All odds are correct at the time of publication and are subject to change.

Cavaliers vs. 76ers Picks

Our model's strongest edge in today's Cavaliers vs. 76ers matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best NBA picks for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Cavaliers vs. 76ers Player Props

Betting on Cleveland vs. Philadelphia NBA prop bets? We use the best information available to project how each team's leading players will perform at Wells Fargo Center.

Donovan Mitchell is expected to lead the Cavaliers in scoring, while Tyrese Maxey is projected to be the top scorer for the 76ers.

Donovan Mitchell 2025.
Donovan Mitchell is projected to be one of the top scorers in tonight's game.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Projected Box Scores for Every NBA Game
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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily NBA betting content, including the free picks featured below.

Conclusion

We predict the Cavaliers, with a 76% win probability, will likely beat the 76ers on Friday.

AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. 76ers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NBA

Keep up with the latest NBA betting news, NBA best bets and NBA parlay picks throughout the season. Plus, our NBA championship odds offer the most accurate projections for the NBA title.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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