Cavaliers vs. Pistons Prediction: Cleveland to Win, Donovan Mitchell Projected for Big Game in Friday's NBA Matchup [3/28/2025]

The Detroit Pistons and Cleveland Cavaliers are scheduled to meet in NBA action at Little Caesars Arena on Friday, starting at 7:00PM ET.

Based on updated simulation results and today’s injury news, Dimers' advanced NBA model (see Dimers Pro for full access) predicts the Cavaliers as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Cleveland-Detroit game 10,000 times," said Damien Souness from Dimers.

"After computing the latest updates and thousands of other inputs, we predict the Cavaliers' chance of winning is 72%, while the Pistons' is 28%."

This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature players like Malik Beasley, Dennis Schroder and Ausar Thompson, while the Cavaliers will rely on Donovan Mitchell, Darius Garland and Evan Mobley.

For expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Cavaliers vs. Pistons predictions page.

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Cavaliers vs. Cavaliers Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Friday's NBA matchup between the Cavaliers and Pistons 10,000 times as part of our NBA predictions coverage.

Our famous predictive model gives the Cavaliers a 72% chance of beating the Pistons. Our predicted final score has the Cavaliers winning 119-112.

According to our model, the Cavaliers (-6.5) have a 51% chance of covering the spread, while the over/under total of 234.5 points has a 54% chance of staying under.

Pre-Game Probabilities

Last Updated: 11:06PM, Mar 28

Spread

Over / Under

Moneyline

Cavaliers

Cavaliers -7.0

51%

49%

-106

-110

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Pistons

Cavaliers CLE

-106

Cavaliers -7.0

51%

49%

See Matchup

Pistons DET

-110

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Cavaliers vs. Pistons Odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Cavaliers vs. Pistons Picks and Best Bets

Our model's biggest edge in today's Cavaliers vs. Pistons matchup is on the spread.

Our expert predictions, matched against the current odds, reveal the best NBA picks and NBA best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Cavaliers vs. Pistons Player Props

Betting on Cavaliers vs. Pistons NBA player props? We use the best information available to project how each team's leading players will perform at Little Caesars Arena.

Donovan Mitchell is expected to lead the Cavaliers in scoring, while Malik Beasley is projected to be the top scorer for the Pistons.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Projected Box Scores for Every NBA Game

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Calling Our Shot's Best Bets

Calling Our Shot produces daily NBA betting content, including the latest best bets featured below.

Cavs vs. Pistons Game-Day Updates and Essential Details

Friday's game between the Pistons and Cavaliers at Little Caesars Arena is scheduled to begin at 7:00PM ET.

• Who: Cleveland Cavaliers vs. Detroit Pistons
• Date: Friday, March 28, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Little Caesars Arena

Dimers.com's comprehensive preview of Friday's Cavaliers vs. Pistons matchup includes our prediction, picks and the latest betting odds.

Before making any Cleveland vs. Detroit picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cavaliers, with a 72% win probability, will likely beat the Pistons on Friday.

AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. Pistons insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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