Clemson vs. Syracuse CFB Prediction and Odds - September 30, 2023

Syracuse squares off with the favored Clemson in College Football action at JMA Wireless Dome on Saturday, beginning at 12:00PM ET.

Dimers' top betting picks for Clemson vs. Syracuse, plus game predictions and best odds, are featured in this article.

This Clemson vs. Syracuse betting preview is sponsored by Bet365, which has a great Bet $1, Get $365 in Bonus Bets offer for new customers.

Who Will Win: Clemson vs. Syracuse

Based on cutting-edge machine learning and data, Dimers.com has simulated Clemson vs. Syracuse 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives Clemson a 67% chance of getting the W against Syracuse.

More: Betting Guide for Clemson vs. Syracuse

Clemson vs. Syracuse Odds

• Spread: Syracuse +7 (+100), Clemson -7 (-110)
• Moneyline: Syracuse +250, Clemson -275
• Total: Over/Under 52 (-110/-110)

Syracuse is the +7 underdog against Clemson, with +100 at PointsBet the best odds currently available.

For the favored Clemson (-7) to cover the spread, FanDuel Sportsbook has the best odds currently on the market at -110.

PointsBet currently has the best moneyline odds for Syracuse at +250, which means you can bet $100 to profit $250, earning a total payout of $350, if it wins.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Clemson at -275, where you can risk $275 to win $100, for a total payout of $375, if it comes out on top.

The Over/Under for total points scored is set at 52 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Syracuse (+7) has a 53% chance of covering the spread, while the 52-point Over/Under has a 54% chance of going Over.

More: Predictions for Every CFB Game

Best Bets: Clemson vs. Syracuse

• Spread: Syracuse +7 @ +100 via PointsBet (53% probability)
• Moneyline: Syracuse @ +250 via PointsBet (4.0% edge) 🔥
• Total: Over 52 @ -110 via PointsBet (54% probability)

Any time you see a 🔥, that means it's one of Dimers' best bets today across all major pro and college sports.

Our best bets are based on complex modeling and gambling intelligence to help you make more informed decisions with the legal sportsbooks in your state.

While Clemson is more likely to win the game, according to DimersBOT, taking Syracuse moneyline is the best option because of the 4.0% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen here at Dimers.com is crucial to achieving long-term profitability.

Clemson vs. Syracuse Prediction

Dimers.com's predicted final score for Clemson vs. Syracuse at JMA Wireless Dome on Saturday has Clemson winning 30-23.

Click or tap on See Matchup to find out more.

Dimers has full betting coverage of this week's Clemson-Syracuse game, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis before Clemson vs. Syracuse on Saturday September 30, 2023.

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Clemson vs. Syracuse 2023

Saturday's action between Syracuse and Clemson in College Football at JMA Wireless Dome is scheduled to commence at 12:00PM ET.

• Who: Clemson vs. Syracuse
• Date: Saturday September 30, 2023
• Time: 12:00PM ET / 9:00AM PT
• Venue: JMA Wireless Dome

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Make Informed Sports Betting Decisions with Dimers

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Clemson vs. Syracuse picks can help you make informed decisions, it's crucial that you gamble responsibly and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More College Football Previews Like This?

So, you liked our Clemson vs. Syracuse betting predictions? Awesome. Did you know our College Football Betting News page has a detailed betting preview for every CFB game the second the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to write the most accurate CFB betting previews and beat the public and the sportsbooks to the punch.

In addition to our leading CFB predictions, Dimers also offers the best CFB prop bets today, projecting passing yards, touchdowns, and more against the top odds available every single day of the CFB season.