Cincinnati vs. South Florida CFB Predictions and Odds - Nov 12, 2021

College Football action continues on Friday at 6:00 PM EST as the favored Cincinnati takes on South Florida at Raymond James Stadium.

Dimers' top betting picks for Cincinnati vs. South Florida, as well as game predictions and best odds, are detailed below.

Who will win Cincinnati vs. South Florida?

Using state-of-the-art machine learning and data, Dimers.com has simulated Friday's Cincinnati-South Florida NCAA Football matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives Cincinnati a 91% chance of winning against South Florida.

MORE: Full betting guide for Cincinnati vs. South Florida

Cincinnati vs. South Florida Point Spread, Moneyline and Over/Under

South Florida is listed as the +24.5 underdog at home to Cincinnati, with -105 at DraftKings Sportsbook the best odds available.

For the favored Cincinnati (-24.5) to cover the spread, PointsBet has the best odds on the market at -105.

PointsBet has the best moneyline odds for South Florida at +1125. That means you can bet $100 to profit $1125, earning a total payout of $1225, if it wins.

Meanwhile, PointsBet also has the best moneyline odds for Cincinnati at -2049, where you can risk $2049 to win $100, for a total payout of $2149, if it comes out on top.

The Over/Under sits at 59.5 with FanDuel Sportsbook, which has the best odds for the Over at -112, as well as the best odds for the Under at -108.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, South Florida (+24.5) is a 53% chance of covering the spread, while the Over/Under total of 59.5 points is a 54% chance of going Under.

Best Bets for Cincinnati vs. South Florida

• Spread: South Florida +24.5 at -105 with DraftKings Sportsbook (53% probability)
• Moneyline: South Florida Win at +1125 with PointsBet (0.5% edge)
• Over/Under: Under 59.5 at -108 with FanDuel Sportsbook (54% probability)

While Cincinnati is more likely to win the game, according to DimersBOT, betting on South Florida moneyline is the best option due to the 0.5% edge found when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges published here at Dimers.com is pivotal to being a profitable bettor in the long run.

MORE: Predictions for every College Football game

Cincinnati vs. South Florida Score Prediction

Dimers.com's predicted final score for Cincinnati vs. South Florida at Raymond James Stadium this Friday has Cincinnati winning 40-17.

Dimers has full coverage of this week's Cincinnati-South Florida game, including pre-game predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for the latest before Cincinnati vs. South Florida on Friday November 12, 2021.

Cincinnati vs. South Florida 2021 CFB Game Info

When does South Florida play Cincinnati in College Football?

• Date: Friday November 12, 2021
• Time: 6:00 PM EST / 3:00 PM PST
• Venue: Raymond James Stadium

Want to join an online sportsbook and start betting on College Football now? Check out the best sportsbook bonus offers in your state.

Want more College Football previews like this?

To get more College Football betting previews like this one for Cincinnati vs. South Florida, all you've gotta do is visit our College Football Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can produce the most comprehensive CFB betting previews out there. We're able to do this by comparing our dynamic and accurate probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.