Reds vs. Giants Prediction: San Francisco Predicted to Win Monday's MLB Matchup [4/7/2025]

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Written by Dave Garofolo

Our expert prediction for Monday's Cincinnati Reds vs San Francisco Giants matchup.

Cincinnati Reds-San Francisco Giants Predictions and Game Preview.
Oracle Park sets the stage for the MLB matchup between the Cincinnati Reds and San Francisco Giants this Monday.

MLB action continues on Monday at 9:45PM ET as the Cincinnati Reds take on the San Francisco Giants at Oracle Park.

Logan Webb (1-0, 3.00 ERA) will get the ball for the Giants, while the Reds have opted for Hunter Greene (0-1, 2.25 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Cincinnati-San Francisco game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Giants are likely to win, with a probability of 58%, compared to the Reds' 42%."

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Reds vs. Giants predictions page.

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Reds vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Monday's MLB game between the Reds and Giants 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Giants a 58% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 63% chance of covering the run line, while the 6.5-run over/under has a 54% chance of going over.

Pre-Game Probabilities
Last Updated: 3:28AM, Apr 8
Moneyline
Over / Under
Run Line
Reds
Win %
43%
57%
Get the best bets with Dimers Pro
See Matchup
Giants
Reds CIN
Win %
43%
57%
See Matchup
Giants SF
Hunter Greene 0-1, 2.25 ERA
Logan Webb 1-0, 3.00 ERA
Get the best bets with Dimers Pro

Reds vs. Giants Odds [4/7/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Reds Giants
Run Line +1.5 (-170) -1.5 (+142)
Moneyline +140 -162
Total o6.5 (-120) u6.5 (+100)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Reds vs. Giants Picks and Best Bets

Our model's strongest edge in today's Reds vs. Giants matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Reds vs. Giants Game-Day Updates and Essential Details

Monday's MLB game between the Giants and Reds at Oracle Park is scheduled to start at 9:45PM ET.

Dimers.com's in-depth preview of Monday's Reds vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. San Francisco picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Giants, with a 58% win probability, will likely beat the Reds on Monday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest predictions for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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