Reds vs. Guardians Prediction: Guardians Predicted to Win Following Latest Data Analysis for Wednesday's MLB Game [9/25/2024]

MLB action continues on Wednesday at 6:40PM ET as the Cincinnati Reds square off with the Cleveland Guardians at Progressive Field.

The Guardians will have Andrew Walters (1-0, 0.00 ERA) as their starting pitcher, up against Jakob Junis (4-0, 2.61 ERA) for the Reds.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Guardians as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Reds-Guardians game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Guardians' chance of winning at 63%, with the Reds at 37%."

Reds vs. Guardians Game-Day Updates and Essential Details

Wednesday's MLB action between the Guardians and Reds at Progressive Field is scheduled to commence at 6:40PM ET.

• Who: Cincinnati Reds vs. Cleveland Guardians
• Date: Wednesday, September 25, 2024
• Time: 6:40PM ET/3:40PM PT
• Venue: Progressive Field
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Guardians and Reds gear at Fanatics
• Live Stream: Watch the game on FuboTV

Dimers.com's full preview of Wednesday's Reds vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Guardians vs. Reds picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

READER EXCLUSIVE: Sign up with code 20BASEBALL at checkout right now to receive 20% off your first month of Dimers Pro! This offer won't last forever.

Reds vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Reds and Guardians 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Guardians a 63% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 56% chance of covering the run line, while the over/under total of 8 runs has a 57% chance of going over.

Reds vs. Guardians Odds [9/25/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Reds	Guardians
Run Line	+1.5 (-175)	-1.5 (+146)
Moneyline	+125	-146
Total	o8 (-104)	u8 (-115)

All odds are correct at the time of publication and are subject to change.

Reds vs. Guardians Picks

Our model's strongest edge in today's Reds vs. Guardians matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks for every game throughout the season.

Unlimited access to our picks, including this one, is available via Dimers Pro.

Calling Our Shot: Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Conclusion

We predict the Guardians, with a 63% win probability, will likely beat the Reds on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay updated with the latest MLB news and our data-led MLB best bets and MLB parlay picks throughout the season. Plus, our World Series odds provide the most up-to-date predictions for the World Series, American League, National League and each division.