Chiefs vs. 49ers Week 7 Prediction and Odds - Oct 23, 2022

The San Francisco 49ers square off with the Kansas City Chiefs in NFL Week 7 action at Levi's Stadium on Sunday, starting at 4:25PM ET.

Dimers' best betting picks for Chiefs vs. 49ers, as well as game predictions, betting odds and touchdown scorer probabilities, are featured below.

Who will win Chiefs vs. 49ers?

Using cutting-edge computer power and data, Dimers.com has simulated Sunday's Chiefs-49ers NFL matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Chiefs a 54% chance of winning against the 49ers in Week 7 of the NFL season.

More: Chiefs vs. 49ers Simulated 10,000 Times

Chiefs vs. 49ers Odds

• Spread: 49ers +0.5 (-107), Chiefs -0.5 (-107)
• Moneyline: 49ers +100, Chiefs -107
• Total: Over/Under 48.5 (-107/-104)

Point Spread, Moneyline and Over/Under

The 49ers are +0.5 underdogs against the Chiefs, with -107 at PointsBet the best odds currently available.

For the favored Chiefs (-0.5) to cover the spread, PointsBet also has the best odds currently on offer at -107.

DraftKings Sportsbook currently has the best moneyline odds for the 49ers at +100, which means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Meanwhile, PointsBet currently has the best moneyline odds for the Chiefs at -107, where you can risk $107 to win $100, for a total payout of $207, if they come out on top.

The Over/Under is set at 48.5 with PointsBet, which currently has the best odds for the Over at -107, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, check out all of the online sportsbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the Chiefs (-0.5) are a 52% chance of covering the spread, while the Over/Under total of 48.5 points is a 51% chance of going Over.

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Best Bets for Chiefs vs. 49ers

• Spread: Chiefs -0.5 @ -107 via PointsBet (52% probability)
• Moneyline: Chiefs @ -107 via PointsBet (54% probability)
• Total: Over 48.5 @ -107 via PointsBet (51% probability)

Dimers' best bets are based on detailed simulations and gambling intelligence to serve you the best possible plays every time.

Chiefs vs. 49ers Prediction

Dimers.com's predicted final score for Kansas City vs. San Francisco at Levi's Stadium in Week 7 has the Chiefs winning 25-24.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Chiefs-49ers matchup in Week 7, including pregame predictions, top betting picks, and live scores.

Chiefs vs. 49ers Player Props

Who will score the first touchdown in Chiefs vs. 49ers? The latest data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Chiefs and 49ers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop picks for Sunday's game.

According to DimersBOT, Kansas City's Travis Kelce is most likely to score the first touchdown in Chiefs vs. 49ers.

DimersBOT gives Kelce a 10.1% chance of scoring the first TD at Levi's Stadium, while the Chiefs TE is a 45.7% chance of scoring an anytime touchdown.

Scroll down for our full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Kansas City Chiefs

• Travis Kelce: 10.1% probability
• Clyde Edwards-Helaire: 6.0% probability
• Marquez Valdes-Scantling: 5.7% probability
• JuJu Smith-Schuster: 5.6% probability
• Mecole Hardman: 5.2% probability

San Francisco 49ers

• Deebo Samuel: 8.7% probability
• Christian McCaffrey: 7.8% probability
• Brandon Aiyuk: 6.6% probability
• Jeff Wilson: 5.7% probability
• George Kittle: 5.5% probability

Anytime Touchdown Scorer Probabilities

Kansas City Chiefs

• Travis Kelce: 45.7% probability
• Marquez Valdes-Scantling: 27.8% probability
• Clyde Edwards-Helaire: 27.6% probability
• Mecole Hardman: 26.6% probability
• JuJu Smith-Schuster: 26.4% probability

San Francisco 49ers

• Deebo Samuel: 40.3% probability
• Christian McCaffrey: 36.9% probability
• Brandon Aiyuk: 31.6% probability
• George Kittle: 28.7% probability
• Jeff Wilson: 27.7% probability

Chiefs-49ers Projected Player Stats

Of the starting quarterbacks, the Chiefs' Patrick Mahomes is projected to have a big game with 282 passing yards, while the 49ers' Jimmy Garoppolo is expected to throw for 258 yards.

Chiefs Starting QB

• Patrick Mahomes: 282 projected yards

49ers Starting QB

• Jimmy Garoppolo: 258 projected yards

Chiefs Rushing

• Isiah Pacheco: 58 projected yards
• Clyde Edwards-Helaire: 34 projected yards
• Patrick Mahomes: 22 projected yards

49ers Rushing

• Christian McCaffrey: 51 projected yards
• Jeff Wilson: 37 projected yards
• Deebo Samuel: 23 projected yards

Chiefs Receiving

• Travis Kelce: 83 projected yards
• JuJu Smith-Schuster: 54 projected yards
• Marquez Valdes-Scantling: 43 projected yards
• Mecole Hardman: 33 projected yards
• Skyy Moore: 22 projected yards

49ers Receiving

• Deebo Samuel: 54 projected yards
• George Kittle: 53 projected yards
• Brandon Aiyuk: 45 projected yards
• Christian McCaffrey: 22 projected yards
• Ray-Ray McCloud: 14 projected yards

Remember, DimersBOT updates often, so keep an eye on this page for the latest betting insights before Chiefs vs. 49ers on Sunday October 23, 2022.

Chiefs vs. 49ers 2022

The NFL Week 7 action between the 49ers and Chiefs at Levi's Stadium is scheduled to start at 4:25PM ET.

• Who: Kansas City Chiefs vs. San Francisco 49ers
• Date: Sunday October 23, 2022
• Time: 4:25PM ET / 1:25PM PT
• Venue: Levi's Stadium

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