White Sox vs. Twins Prediction: Minnesota Predicted to Win Wednesday's MLB Matchup [4/23/2025]

The Minnesota Twins will take on the Chicago White Sox in MLB action at Target Field on Wednesday, starting at 7:40PM ET.

The Twins will start David Festa (0-0, 0.00 ERA), while the White Sox will counter with Bryse Wilson (0-0, 4.50 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Twins as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's CHI White Sox-Minnesota game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Twins' chance of winning at 68%, with the White Sox at 32%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive White Sox vs. Twins predictions page.

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Twins vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Wednesday's MLB game between the White Sox and Twins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Twins a 68% chance of beating the White Sox.

According to our model, the bookies have got it right, and the White Sox and Twins each have a 50% chance of covering the run line, while the 8.5-run over/under has a 51% chance of staying under.

Pre-Game Probabilities

Last Updated: 11:28PM, Apr 23

Moneyline

Over / Under

Run Line

White Sox

Win %

32%

68%

+225

-250

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Twins

White Sox CWS

+225

Win %

32%

68%

See Matchup

Twins MIN

-250

Bryse Wilson 0-0, 4.50 ERA

David Festa 0-0, 0.00 ERA

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White Sox vs. Twins Odds [4/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Twins Picks and Best Bets

Our model's biggest edge in today's White Sox vs. Twins matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

White Sox vs. Twins Game-Day Updates and Essential Details

Wednesday's MLB game between the Twins and White Sox at Target Field is scheduled to begin at 7:40PM ET.

• Who: Chicago White Sox vs. Minnesota Twins
• Date: Wednesday, April 23, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Target Field

Dimers.com's comprehensive preview of Wednesday's White Sox vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Twins, with a 68% win probability, will likely beat the White Sox on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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