White Sox vs. Twins Prediction: Minnesota Predicted to Win Tuesday's MLB Matchup [4/22/2025]

The Minnesota Twins will square off with the Chicago White Sox in MLB action at Target Field on Tuesday, beginning at 7:40PM ET.

The Twins will send Bailey Ober (1-1, 6.16 ERA) to the mound, up against Davis Martin (1-2, 4.84 ERA) for the White Sox.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Twins as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's CHI White Sox-Minnesota game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Twins with a win probability of 66%, compared to 34% for the White Sox."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive White Sox vs. Twins predictions page.

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Twins vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB game between the White Sox and Twins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Twins a 66% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 52% chance of covering the run line, while the 8.5-run over/under has a 51% chance of staying under.

Pre-Game Probabilities

Last Updated: 11:31PM, Apr 22

Moneyline

Over / Under

Run Line

White Sox

Win %

34%

66%

+230

-250

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Twins

White Sox CWS

+230

Win %

34%

66%

See Matchup

Twins MIN

-250

Davis Martin 1-2, 4.84 ERA

Bailey Ober 1-1, 6.16 ERA

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White Sox vs. Twins Odds [4/22/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Twins Picks and Best Bets

Our model's strongest edge in today's White Sox vs. Twins matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

White Sox vs. Twins Game-Day Updates and Essential Details

Tuesday's MLB game between the Twins and White Sox at Target Field is scheduled to start at 7:40PM ET.

• Who: Chicago White Sox vs. Minnesota Twins
• Date: Tuesday, April 22, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Target Field

Dimers.com's in-depth preview of Tuesday's White Sox vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Twins, with a 66% win probability, will likely beat the White Sox on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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