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White Sox vs. Red Sox Prediction: Boston Predicted to Win Sunday's MLB Matchup [4/20/2025]
Our expert prediction for Sunday's Chicago White Sox vs Boston Red Sox matchup.

The Boston Red Sox and Chicago whitesox are scheduled to meet in MLB action at Fenway Park on Sunday, starting at 1:35PM ET.
Tanner Houck (0-2, 9.16 ERA) will be on the bump for the Red Sox, while the White Sox are going with Sean Burke (1-3, 7.56 ERA).
Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Red Sox as the most likely winner of today's game.
"Using the most recent data, our experts ran 10,000 simulations of Sunday's CHI White Sox-Boston game," said Dimers' Chief Content Officer, Nick Slade.
"After accounting for recent updates and other variables, our prediction shows the Red Sox with a win probability of 69%, while the White Sox have 31%."
For a closer look at Sunday's matchup, including best bets and picks, visit our interactive White Sox vs. Red Sox predictions page.
White Sox vs. White Sox Prediction: Who Will Win, Cover the Run Line?
Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's MLB game between the White Sox and Red Sox 10,000 times as part of our MLB predictions coverage.
Our independent predictive model gives the Red Sox a 69% chance of beating the White Sox.
According to our model, the Red Sox (-1.5) have a 51% chance of covering the run line, while the over/under total of 9.5 runs has a 58% chance of staying under.
White Sox vs. Red Sox Odds [4/20/2025]
We have researched the best MLB odds in America for this game, which are listed here:
Bet Type | White Sox | Red Sox |
---|---|---|
Run Line | +1.5 (+120) | -1.5 (-135) |
Moneyline | +240 | -290 |
Total | o9.5 (-110) | u9.5 (-106) |
All odds are correct at the time of publication and are subject to change.
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White Sox vs. Red Sox Picks and Best Bets
Our model's strongest edge in today's White Sox vs. Red Sox matchup is on the run line.
Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free MLB Picks
Calling Our Shot produces daily MLB betting content, including the predictions featured below.
White Sox vs. Red Sox Game-Day Updates and Essential Details
Sunday's MLB action between the Red Sox and White Sox at Fenway Park is scheduled to commence at 1:35PM ET.
- Who: Chicago White Sox vs. Boston Red Sox
- Date: Sunday, April 20, 2025
- Time: 1:35PM ET/10:35AM PT
- Venue: Fenway Park
Dimers.com's in-depth preview of Sunday's White Sox vs. Red Sox matchup includes our prediction, picks and the latest betting odds.
Before making any CHI White Sox vs. Boston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
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- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
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Conclusion
We predict the Red Sox, with a 69% win probability, will likely beat the White Sox on Sunday.
AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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