White Sox vs. Red Sox Prediction: Boston Predicted to Win Sunday's MLB Matchup [4/20/2025]

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Written by Jason Bevilacqua

Our expert prediction for Sunday's Chicago White Sox vs Boston Red Sox matchup.

Chicago White Sox-Boston Red Sox Predictions and Game Preview.
Fenway Park sets the stage for the MLB matchup between the Chicago White Sox and Boston Red Sox this Sunday.

The Boston Red Sox and Chicago whitesox are scheduled to meet in MLB action at Fenway Park on Sunday, starting at 1:35PM ET.

Tanner Houck (0-2, 9.16 ERA) will be on the bump for the Red Sox, while the White Sox are going with Sean Burke (1-3, 7.56 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Red Sox as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's CHI White Sox-Boston game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Red Sox with a win probability of 69%, while the White Sox have 31%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive White Sox vs. Red Sox predictions page.

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White Sox vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's MLB game between the White Sox and Red Sox 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Red Sox a 69% chance of beating the White Sox.

According to our model, the Red Sox (-1.5) have a 51% chance of covering the run line, while the over/under total of 9.5 runs has a 58% chance of staying under.

Pre-Game Probabilities
Last Updated: 6:28PM, Apr 20
Moneyline
Over / Under
Run Line
White Sox
Win %
31%
69%
Get the best bets with Dimers Pro
See Matchup
Red Sox
White Sox CWS
Win %
31%
69%
See Matchup
Red Sox BOS
Sean Burke 1-3, 7.56 ERA
Tanner Houck 0-2, 9.16 ERA
Get the best bets with Dimers Pro

White Sox vs. Red Sox Odds [4/20/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type White Sox Red Sox
Run Line +1.5 (+120) -1.5 (-135)
Moneyline +240 -290
Total o9.5 (-110) u9.5 (-106)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Red Sox Picks and Best Bets

Our model's strongest edge in today's White Sox vs. Red Sox matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

White Sox vs. Red Sox Game-Day Updates and Essential Details

Sunday's MLB action between the Red Sox and White Sox at Fenway Park is scheduled to commence at 1:35PM ET.

Dimers.com's in-depth preview of Sunday's White Sox vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Boston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Red Sox, with a 69% win probability, will likely beat the White Sox on Sunday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most accurate predictions for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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