White Sox vs. Red Sox Prediction: Boston Predicted to Win Friday's MLB Matchup [4/18/2025]

MLB action continues on Friday at 7:10PM ET as the Chicago White Sox face off with the favored Boston Red Sox at Fenway Park.

Hunter Dobbins (1-0, 3.60 ERA) will be on the bump for the Red Sox, up against Martín Pérez (1-0, 1.59 ERA) for the White Sox.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Red Sox as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's CHI White Sox-Boston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Red Sox' chance of winning is 62%, while the White Sox' is 38%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive White Sox vs. Red Sox predictions page.

Get 20% off Dimers Pro With Code 20BASEBALL

Get Dimers Pro

White Sox vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the result of Friday's MLB game between the White Sox and Red Sox 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Red Sox a 62% chance of beating the White Sox.

According to our model, the White Sox (+1.5) have a 56% chance of covering the run line, while the over/under total of 9.5 runs has a 53% chance of staying under.

Pre-Game Probabilities

Last Updated: 11:28PM, Apr 18

Moneyline

Over / Under

Run Line

White Sox

Win %

38%

62%

+200

-225

Get the best bets with Dimers Pro

See Matchup

Get Dimers Pro

Red Sox

White Sox CWS

+200

Win %

38%

62%

See Matchup

Red Sox BOS

-225

Martín Pérez 1-0, 1.59 ERA

Hunter Dobbins 1-0, 3.60 ERA

Get the best bets with Dimers Pro

Get Dimers Pro

White Sox vs. Red Sox Odds [4/18/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

White Sox vs. Red Sox Picks and Best Bets

Our model's strongest edge in today's White Sox vs. Red Sox matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Unlock Every White Sox-Red Sox Pick

Get Dimers Pro

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

White Sox vs. Red Sox Game-Day Updates and Essential Details

Friday's MLB game between the Red Sox and White Sox at Fenway Park is scheduled to begin at 7:10PM ET.

• Who: Chicago White Sox vs. Boston Red Sox
• Date: Friday, April 18, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Fenway Park

Dimers.com's full preview of Friday's White Sox vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Boston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Conclusion

We predict the Red Sox, with a 62% win probability, will likely beat the White Sox on Friday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest probabilities for the World Series, American League, National League and each division.