Chelsea vs. Southampton Prediction, Odds, Premier League Picks [2/25/2025]

Chelsea will square off with Southampton in Premier League action at Stamford Bridge on Tuesday, beginning at 3:15PM ET.

Based on updated simulation results, Dimers' proven Premier League model (see Dimers Pro for full access) predicts Chelsea as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Chelsea-Southampton game," said Jason Bevilacqua from Dimers.

"After incorporating the most recent updates and numerous additional inputs, our prediction gives Chelsea a 78.8% chance of winning, Southampton a 7.8% chance, and a 13.3% chance of a draw."

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Chelsea vs. Southampton predictions page.

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Chelsea vs. Southampton Prediction: Who Will Win?

Using innovative machine learning and data analysis, we have simulated the outcome of Tuesday's Premier League match between Chelsea and Southampton 10,000 times as part of our Premier League predictions coverage.

Our famous predictive model suggests a 78.8% chance of Chelsea winning, a 7.8% chance for Southampton, and a 13.3% chance of a draw.

Pre-Game Probabilities

Last Updated: 7:15PM, Feb 25

Moneyline

Correct Score

Win %

Southampton SOT

7.8%

+1700

Draw

13.3%

+800

Chelsea CFC

78.8%

-625

FanDuel

BetMGM

Caesars

DraftKings

bet365

BetRivers

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Chelsea vs. Southampton Odds

We have sourced the best Premier League odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Chelsea vs. Southampton Picks and Best Bets

Our model's strongest edge in today's Chelsea vs. Southampton matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best Premier League picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Chelsea vs. Southampton: Correct Score and BTTS Predictions

Here are the top three most likely final scores according to our model, with a 2-0 Chelsea win being the most probable:

When it comes to the both teams to score (BTTS) market, we project a 50.6% chance of the yes hitting, and a 49.4% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations.

Chelsea vs. Southampton Game-Day Updates and Essential Details

Tuesday's Premier League action between Chelsea and Southampton at Stamford Bridge is scheduled to begin in the USA at 3:15PM ET.

• Who: Chelsea vs. Southampton
• Date: Tuesday, February 25, 2025
• Time: 3:15PM ET/12:15PM PT
• Venue: Stamford Bridge

Dimers.com's comprehensive preview of Tuesday's Chelsea vs. Southampton matchup includes our prediction, picks and the latest betting odds.

Before making any Southampton vs. Chelsea picks, be sure to check out the latest Premier League predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Chelsea has a 78.8% win probability on Tuesday, Southampton has a 7.8% win probability, and there is a 13.3% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Chelsea vs. Southampton insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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