Chargers vs. Colts Week 16 Prediction and Odds - Dec 26, 2022

The Indianapolis Colts and Los Angeles Chargers clash in Week 16 of the NFL season at Lucas Oil Stadium on Monday, with kickoff at 8:15PM ET.

Dimers' best betting picks for Chargers vs. Colts, plus game predictions, betting odds and touchdown scorer probabilities, are featured in this article.

Who will win Chargers vs. Colts?

Based on cutting-edge computer power and data, Dimers.com has simulated Monday's Chargers-Colts NFL game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Chargers a 64% chance of winning against the Colts in Week 16 of the NFL season.

More: Chargers vs. Colts Simulated 10K Times

Chargers vs. Colts Current Odds

• Spread: Colts +3.5 (-110), Chargers -3.5 (-110)
• Moneyline: Colts +170, Chargers -196
• Total: Over/Under 44.5 (-110/-106)

Point Spread, Moneyline and Over/Under

The Colts are currently +3.5 underdogs against the Chargers, with -110 at Caesars Sportsbook the best odds currently available.

For the favored Chargers (-3.5) to cover the spread, Caesars Sportsbook also has the best odds currently on the market at -110.

DraftKings Sportsbook currently has the best moneyline odds for the Colts at +170, which means you can bet $100 to profit $170, earning a total payout of $270, if they win.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Chargers at -196, where you can risk $196 to win $100, for a total payout of $296, if they come out on top.

The Over/Under sits at 44.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -106.

As always, check out all of the legal sportbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Chargers and Colts are a 50% chance of covering the spread, while the Over/Under total of 44.5 points is also considered an equal 50-50 chance of hitting.

More: Predictions for Every NFL Week 16 Game

Best Bets for Chargers vs. Colts

• Spread: Chargers -3.5 @ -110 via Caesars Sportsbook (50% probability)
• Moneyline: Colts @ +170 via DraftKings Sportsbook
• Total: Under 44.5 @ -106 via FanDuel Sportsbook (50% probability)

Dimers' best bets are based on complex modeling and wagering intelligence to serve you the best possible plays every time.

While the Chargers are more likely to win the game, according to DimersBOT, betting on the Colts moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers is pivotal to achieving long-term profitability as a sports bettor.

Chargers vs. Colts Prediction

Dimers.com's predicted final score for LA Chargers vs. Indianapolis at Lucas Oil Stadium in Week 16 has the Chargers winning 24-20.

Click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's Chargers-Colts matchup in Week 16, including pregame predictions, free picks, and live win probabilities.

Chargers vs. Colts Player Props

Who will score an anytime touchdown in Chargers vs. Colts? The latest data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Chargers and Colts, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop bets for Monday's game.

According to DimersBOT, Los Angeles' Austin Ekeler is most likely to score the first TD in Chargers vs. Colts.

DimersBOT gives Ekeler a 12.6% chance of getting in for six first at Lucas Oil Stadium, while the Chargers RB is a 49.1% chance of reaching the end zone at any point during the game.

Scroll down for our full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Los Angeles Chargers

• Austin Ekeler: 12.6% probability
• Keenan Allen: 10.2% probability
• Mike Williams: 7.7% probability
• Gerald Everett: 5.6% probability
• Justin Herbert: 4.9% probability

Indianapolis Colts

• Zack Moss: 8.5% probability
• Michael Pittman: 6.7% probability
• Parris Campbell: 6.1% probability
• Nick Foles: 5.9% probability
• Deon Jackson: 5.2% probability

Anytime Touchdown Scorer Probabilities

Los Angeles Chargers

• Austin Ekeler: 49.1% probability
• Keenan Allen: 41.4% probability
• Mike Williams: 33.5% probability
• Gerald Everett: 24.5% probability
• Justin Herbert: 21.3% probability

Indianapolis Colts

• Zack Moss: 36.2% probability
• Michael Pittman: 30.5% probability
• Parris Campbell: 27.1% probability
• Nick Foles: 26.9% probability
• Deon Jackson: 24.0% probability

Chargers-Colts Projected Player Stats

Of the starting quarterbacks, the Chargers' Justin Herbert is projected to have a big game with 290 passing yards, while the Colts' Nick Foles is expected to throw for 228 yards.

Chargers Starting QB

• Justin Herbert: 290 projected yards

Colts Starting QB

• Nick Foles: 228 projected yards

Chargers Rushing

• Austin Ekeler: 59 projected yards
• Joshua Kelley: 22 projected yards
• Justin Herbert: 13 projected yards

Colts Rushing

• Zack Moss: 47 projected yards
• Deon Jackson: 36 projected yards
• Nick Foles: 8 projected yards

Chargers Receiving

• Keenan Allen: 62 projected yards
• Mike Williams: 61 projected yards
• Austin Ekeler: 44 projected yards
• Gerald Everett: 33 projected yards
• Joshua Palmer: 32 projected yards

Colts Receiving

• Michael Pittman: 80 projected yards
• Parris Campbell: 39 projected yards
• Jelani Woods: 26 projected yards
• Alec Pierce: 25 projected yards
• Deon Jackson: 20 projected yards

Don't forget, DimersBOT updates frequently, so check this article for the latest betting analysis before Chargers vs. Colts on Monday December 26, 2022.

Chargers vs. Colts 2022

The NFL Week 16 game between the Colts and Chargers at Lucas Oil Stadium is scheduled to commence at 8:15PM ET.

• Who: Los Angeles Chargers vs. Indianapolis Colts
• Date: Monday December 26, 2022
• Time: 8:15PM ET / 5:15PM PT
• Venue: Lucas Oil Stadium

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