Chargers vs. Cardinals Week 12 Prediction and Odds - Nov 27, 2022

The Arizona Cardinals and Los Angeles Chargers are scheduled to meet in Week 12 of the NFL season at State Farm Stadium on Sunday, with kickoff at 4:05PM ET.

Dimers' free betting picks for Chargers vs. Cardinals, plus game predictions, betting odds and projected player stats, are featured in this article.

Who will win Chargers vs. Cardinals?

Based on high-tech machine learning and data, Dimers.com has simulated Sunday's Chargers-Cardinals NFL matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Chargers a 59% chance of winning against the Cardinals in Week 12 of the NFL season.

More: Full Betting Guide for Chargers vs. Cardinals

Chargers vs. Cardinals Odds

• Spread: Cardinals +2 (-105), Chargers -2 (-125)
• Moneyline: Cardinals +130, Chargers -135
• Total: Over/Under 48.5 (-110/-105)

Point Spread, Moneyline and Over/Under

The Cardinals are +2 underdogs against the Chargers, with -105 at BetMGM the best odds currently available.

For the favored Chargers (-2) to cover the spread, BetMGM also has the best odds currently on offer at -125.

DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at +130. That means you can bet $100 to profit $130, earning a total payout of $230, if they win.

Elsewhere, PointsBet currently has the best moneyline odds for the Chargers at -135, where you can risk $135 to win $100, for a total payout of $235, if they come out on top.

The Over/Under sits at 48.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best NFL odds and lines.

According to DimersBOT, the Chargers (-2) are a 56% chance of covering the spread, while the Over/Under total of 48.5 points is a 51% chance of going Over.

More: Best Prop Bets Today

Best Bets for Chargers vs. Cardinals

• Spread: Chargers -2 @ -125 via BetMGM (56% probability)
• Moneyline: Chargers @ -135 via PointsBet (59% probability)
• Total: Over 48.5 @ -110 via Caesars Sportsbook (51% probability)

Dimers' best bets are based on detailed modeling and betting expertise to serve you the best possible plays 24/7.

Chargers vs. Cardinals Prediction

Dimers.com's predicted final score for LA Chargers vs. Arizona at State Farm Stadium in Week 12 has the Chargers winning 25-23.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Chargers-Cardinals matchup in Week 12, including pregame predictions, top betting picks, and live win probabilities.

Chargers vs. Cardinals Player Props

Who will score an anytime touchdown in Chargers vs. Cardinals? The latest data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Chargers and Cardinals, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you discover the best prop picks for Sunday's game.

According to DimersBOT, Los Angeles' Austin Ekeler is most likely to score the first touchdown in Chargers vs. Cardinals.

DimersBOT gives Ekeler a 13.8% chance of getting in for six first at State Farm Stadium, while the Chargers RB is a 56.6% chance of registering an anytime touchdown.

Scroll down for the full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Los Angeles Chargers

• Austin Ekeler: 13.8% probability
• Keenan Allen: 8.9% probability
• Joshua Palmer: 6.8% probability
• Gerald Everett: 6.5% probability
• DeAndre Carter: 5.8% probability

Arizona Cardinals

• James Conner: 11.5% probability
• DeAndre Hopkins: 9.9% probability
• Kyler Murray: 7.3% probability
• Marquise Brown: 4.7% probability
• Trey McBride: 4.0% probability

Anytime Touchdown Scorer Probabilities

Los Angeles Chargers

• Austin Ekeler: 56.6% probability
• Keenan Allen: 39.9% probability
• Joshua Palmer: 32.5% probability
• Gerald Everett: 31.0% probability
• DeAndre Carter: 28.0% probability

Arizona Cardinals

• James Conner: 49.4% probability
• DeAndre Hopkins: 44.0% probability
• Kyler Murray: 34.0% probability
• Marquise Brown: 23.9% probability
• Trey McBride: 20.9% probability

Chargers-Cardinals Projected Player Stats

Of the starting quarterbacks, the Chargers' Justin Herbert is projected to have a big game with 291 passing yards. The Cardinals' Kyler Murray is expected to throw for a whopping 261 yards.

Chargers Starting QB

• Justin Herbert: 291 projected yards

Cardinals Starting QB

• Kyler Murray: 261 projected yards

Chargers Rushing

• Austin Ekeler: 59 projected yards
• Joshua Kelley: 19 projected yards
• Isaiah Spiller: 14 projected yards

Cardinals Rushing

• James Conner: 57 projected yards
• Kyler Murray: 33 projected yards
• Keaontay Ingram: 13 projected yards

Chargers Receiving

• Keenan Allen: 59 projected yards
• Joshua Palmer: 44 projected yards
• DeAndre Carter: 40 projected yards
• Gerald Everett: 35 projected yards
• Austin Ekeler: 31 projected yards

Cardinals Receiving

• DeAndre Hopkins: 85 projected yards
• Trey McBride: 37 projected yards
• Marquise Brown: 33 projected yards
• James Conner: 28 projected yards
• A.J. Green: 25 projected yards

Remember, DimersBOT updates regularly, so keep checking this article for any changes to our betting analysis before Chargers vs. Cardinals on Sunday November 27, 2022.

Chargers vs. Cardinals 2022

The NFL Week 12 matchup between the Cardinals and Chargers at State Farm Stadium is scheduled to start at 4:05PM ET.

• Who: Los Angeles Chargers vs. Arizona Cardinals
• Date: Sunday November 27, 2022
• Time: 4:05PM ET / 1:05PM PT
• Venue: State Farm Stadium

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