CFB Best Bets, Picks and Analysis For Tennessee vs. Pittsburgh on September 10, 2022

The Tennessee Volunteers look to get their revenge against the Pittsburgh Panthers after last year's shootout in Knoxville. The Volunteers fell short at home against Kenny Pickett and the Panthers in a 41-34 defeat. But now, both teams are 1-0 after winning in Week 1 and that adds even more juice to this rematch.

Tennessee took down Ball State, 59-10. Meanwhile, Pitt beat rival West Virginia in the Backyard Brawl, 38-31. This game is in Pittsburgh and will kick off at 3:30PM ET from Acrisure Stadium.

This should be an exciting match-up for both viewers and bettors, so make sure you keep reading to check out our Pittsburgh vs. Tennessee betting preview. 

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For the most up to date CFB computer picks, check out our interactive predictions for Tennessee vs. Pittsburgh. It's constantly updating based on hundreds of different data points.

Tennessee vs. Pittsburgh  Best Bets, Predictions and Analysis

Spread Breakdown

The loss of star quarterback Kenny Pickett and offensive coordinator Mark Whipple was evident in Pitt’s opening game. Head coach Pat Narduzzi wants to run the ball more despite being unsuccessful against West Virginia. Pitt averaged 2.0 yards per rush in its opener. The key for the Tennessee defense is to stop the run. Pitt quarterback Kedon Slovis isn’t a threat with his legs, so if Tennessee isn't getting gashed on the ground, it has a great chance of winning.

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The Tennessee offense is one of the more explosive offenses in the country. Quarterback Hendon Hooker is incredibly efficient throwing the football. The Vols can also run the ball when needed. They had 236 rushing yards against Ball State. The Pitt defense struggled against a balanced West Virginia offensive attack in its opener. Tennessee should not have an issue moving the football.

The spread for this game is at -6.5 in favor of Tennessee. The DimersBOT likes Pitt to keep it closer than expected and we agree with the model here. Tennessee is the better team overall and the Vols offense is nothing to mess with. But home-field advantage will play a big factor in this game. Give us Pitt plus the points and look for Slovis to make big throws when the Panthers need him most.

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Over/Under Breakdown

These two teams are definitely capable of putting up points. This game will likely come down to who can make stops inside the red zone. These two teams shouldn’t have any trouble moving the football, but once the field shrinks, who will be able to score six instead of settling for three?

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The point total is set at 67 for this game. That is super high considering that these defenses are both good. The offenses will be the main story, but don’t be shocked to see the defenses come up with some big plays. We like the Under here at 67 points. The DimersBOT agrees with that bet.

Best Bet: Volunteers vs. Panthers

The Under 67 points is too good not to take. That is a lot of points for these teams to score, especially in a hostile environment for Tennessee. This game will be high scoring, but not quite as high as Vegas thinks.

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