Cardinals vs. Pirates Prediction and Odds - Sep 10, 2022

The Pittsburgh Pirates and St. Louis Cardinals are scheduled to meet in MLB at PNC Park on Saturday, starting at 7:35PM ET.

JT Brubaker (3-11, 4.35 ERA) will get the ball for the Pirates, while the Cardinals will counter with Jack Flaherty (0-1, 4.15 ERA).

Dimers' free betting picks for Cardinals vs. Pirates, plus game predictions and best odds, are detailed below.

Who will win Cardinals vs. Pirates?

Based on cutting-edge machine learning and data, Dimers.com has simulated Saturday's Cardinals-Pirates MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Cardinals a 62% chance of beating the Pirates.

More: Cardinals vs. Pirates Simulated 10K Times

Cardinals vs. Pirates Current Odds

• Run Line: Pirates +1.5 (-105), Cardinals -1.5 (-110)
• Moneyline: Pirates +158, Cardinals -180
• Total: Over/Under 7.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Pirates are currently +1.5 underdogs versus the Cardinals, with -105 at DraftKings Sportsbook the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -110.

FanDuel Sportsbook currently has the best moneyline odds for the Pirates at +158. That means you can bet $100 to profit $158, earning a total payout of $258, if they win.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at -180, where you can risk $180 to win $100, for a total payout of $280, if they come out on top.

The Over/Under is set at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at -105.

As always, make sure you check all of the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 51% chance of covering the run line, while the 7.5-run Over/Under is a 54% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Cardinals vs. Pirates

• Run Line: Pirates +1.5 @ -105 via DraftKings Sportsbook (51% probability)
• Moneyline: Pirates @ +158 via FanDuel Sportsbook
• Total: Over 7.5 @ -110 via DraftKings Sportsbook (54% probability)

Our best bets are based on detailed simulations and betting intelligence to bring you the best possible plays 24/7/365.

While the Cardinals are more likely to win the game, according to DimersBOT, betting on the Pirates moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers is crucial to being a profitable sports bettor in the long run.

Cardinals vs. Pirates Probabilities

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Dimers has full betting coverage of Saturday's Cardinals-Pirates matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so refresh this page for the latest betting analysis before Cardinals vs. Pirates on Saturday September 10, 2022.

Cardinals vs. Pirates 2022 Game Info

Saturday's game between the Pirates and Cardinals at PNC Park is scheduled to begin at 7:35PM ET.

• Who: St. Louis Cardinals vs. Pittsburgh Pirates
• Date: Saturday September 10, 2022
• Time: 7:35PM ET / 4:35PM PT
• Venue: PNC Park

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Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.