Cardinals vs. Nationals Prediction for MLB Wednesday [6/21/2023]

The Washington Nationals and St. Louis Cardinals meet in MLB action at Nationals Park on Wednesday, starting at 4:05PM ET.

The Nationals will start Trevor Williams (3-4, 4.50 ERA), while the Cardinals will counter with Miles Mikolas (4-4, 4.36 ERA).

Dimers' free betting picks for Cardinals vs. Nationals, as well as game predictions and betting odds, are detailed in this article.

Who Will Win: Cardinals vs. Nationals

Using advanced machine learning and data, Dimers.com has simulated Wednesday's Cardinals-Nationals MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Cardinals a 56% chance of beating the Nationals.

More: Cardinals vs. Nationals Simulated 10K Times

Cardinals vs. Nationals Odds [6/21]

• Run Line: Nationals +1.5 (-115), Cardinals -1.5 (+106)
• Moneyline: Nationals +135, Cardinals -155
• Total: Over/Under 9 (+100/-110)

The Nationals are listed as +1.5 underdogs against the Cardinals, with -115 at DraftKings Sportsbook the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +106.

BetMGM currently has the best moneyline odds for the Nationals at +135. That means you can bet $100 to profit $135, earning a total payout of $235, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at -155, where you can risk $155 to win $100, for a total payout of $255, if they come out on top.

The Over/Under for total runs scored is set at 9 with BetMGM, which currently has the best odds for the Over at +100, while DraftKings Sportsbook currently has the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Nationals (+1.5) have a 56% chance of covering the run line, while the 9-run Over/Under has a 53% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets: Cardinals vs. Nationals

• Run Line: Nationals +1.5 @ -115 via DraftKings Sportsbook (56% probability)
• Moneyline: Nationals @ +135 via BetMGM (1.5% edge)
• Total: Over 9 @ +100 via BetMGM (53% probability)

Dimers' best bets are based on world-class modeling and wagering expertise to serve you the best possible plays 24/7/365.

While the Cardinals are more likely to win the game, according to DimersBOT, taking the Nationals moneyline is the best option because of the 1.5% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers.com is crucial to being a profitable bettor in the long run.

Cardinals vs. Nationals Prediction

Dimers.com predicts that the Cardinals are more likely to beat the Nationals at Nationals Park on Wednesday.

This prediction is backed by extensive data-driven analysis, with the Cardinals boasting a 56% probability of winning after conducting 10,000 simulations of the game.

Click or tap on See Matchup to find out more.

Dimers has full coverage of Wednesday's Cardinals-Nationals game, including pregame predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep an eye on this page for any changes to our betting insights ahead of Cardinals vs. Nationals on Wednesday June 21, 2023.

Cardinals vs. Nationals 2023

Wednesday's MLB matchup between the Nationals and Cardinals at Nationals Park is scheduled to begin at 4:05PM ET.

• Who: St. Louis Cardinals vs. Washington Nationals
• Date: Wednesday June 21, 2023
• Time: 4:05PM ET / 1:05PM PT
• Venue: Nationals Park

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Make Informed Sports Betting Decisions Today

Dimers' picks and predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Cardinals vs. Nationals predictions can help you make informed decisions, it's crucial that you only bet what you can afford to lose and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What MLB Games Are on Today?

The Cardinals and Nationals aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for every single MLB matchup via our MLB predictions. Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

In addition to our leading MLB predictions, Dimers also offers the best MLB prop bets today, projecting home runs, RBIs, and more against the best odds available every day of the MLB season.

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the World Series, with our data-driven probabilities compared to the best odds on the market.