Cardinals vs. Diamondbacks Prediction and Odds - Aug 21, 2022

The Arizona Diamondbacks take on the St. Louis Cardinals in MLB action at Chase Field on Sunday, beginning at 4:10PM ET.

Merrill Kelly (10-5, 2.81 ERA) will get the ball for the Diamondbacks, up against José Quintana (4-5, 3.38 ERA) for the Cardinals.

Dimers' top betting picks for Cardinals vs. Diamondbacks, as well as game predictions and best odds, are featured in this article.

Who will win Cardinals vs. Diamondbacks?

Based on advanced computer power and data, Dimers.com has simulated Sunday's Cardinals-Diamondbacks MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Cardinals a 55% chance of beating the Diamondbacks.

More: Full Betting Guide for Cardinals vs. Diamondbacks

Cardinals vs. Diamondbacks Game Odds

• Run Line: Diamondbacks +1.5 (-154), Cardinals -1.5 (+135)
• Moneyline: Diamondbacks +112, Cardinals -125
• Total: Over/Under 7.5 (-105/-105)

Run Line, Moneyline and Over/Under

The Diamondbacks are +1.5 underdogs against the Cardinals, with -154 at FanDuel Sportsbook the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +135.

FanDuel Sportsbook currently has the best moneyline odds for the Diamondbacks at +112. That means you can bet $100 to profit $112, earning a total payout of $212, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Cardinals at -125, where you can risk $125 to win $100, for a total payout of $225, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with PointsBet, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at -105.

As always, check out all the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Diamondbacks (+1.5) are a 58% chance of covering the run line, while the Over/Under total of 7.5 runs is a 57% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Cardinals vs. Diamondbacks

• Run Line: Cardinals -1.5 @ +135 via BetMGM
• Moneyline: Cardinals @ -125 via BetMGM (55% probability)
• Total: Over 7.5 @ -105 via PointsBet (57% probability) 🔥

If you see a 🔥, you know you've found one of Dimers' best bets of the day across any sport.

Our best bets are based on complex simulations and betting expertise to bring you the best possible plays every time.

Even though the Diamondbacks are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Cardinals vs. Diamondbacks Prediction

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for St. Louis vs. Arizona, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Sunday's Cardinals-Diamondbacks matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this article for any changes to our betting insights before Cardinals vs. Diamondbacks on Sunday August 21, 2022.

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Cardinals vs. Diamondbacks 2022 Game Info

Sunday's matchup between the Diamondbacks and Cardinals at Chase Field is scheduled to commence at 4:10PM ET.

• Who: Arizona Diamondbacks vs. St. Louis Cardinals
• Date: Sunday August 21, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: Chase Field

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What other MLB games are on today?

The Cardinals and Diamondbacks aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single MLB matchup via our MLB Predictions page.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.