Cardinals vs. Cubs Prediction for MLB Friday [7/21/2023]

The Chicago Cubs will take on the St. Louis Cardinals in MLB action at Wrigley Field on Friday, starting at 2:20PM ET.

The Cubs will have Justin Steele (9-3, 2.96 ERA) as their starting pitcher, up against Jack Flaherty (7-5, 4.29 ERA) for the Cardinals.

Dimers' top betting picks for Cardinals vs. Cubs, as well as game predictions and best odds, are featured below.

Who Will Win: Cardinals vs. Cubs

Based on cutting-edge computer power and data, Dimers.com has simulated Friday's Cardinals-Cubs MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Cubs a 56% chance of getting the W against the Cardinals.

More: Cardinals vs. Cubs Simulated 10,000 Times

Cardinals vs. Cubs Odds [7/21]

• Run Line: Cubs -1.5 (+152), Cardinals +1.5 (-165)
• Moneyline: Cubs -135, Cardinals +120
• Total: Over/Under 8.5 (-105/-115)

The Cubs are -1.5 favorites versus the Cardinals, with +152 at FanDuel Sportsbook the best odds currently available.

For the underdog Cardinals (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -165.

BetMGM currently has the best moneyline odds for the Cubs at -135. That means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under is set at 8.5 with BetMGM, which currently has the best odds for the Over at -105, as well as the best odds for the Under at -115.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) have a 63% chance of covering the run line, while the 8.5-run Over/Under has a 55% chance of going Under.

More: Predictions for Every MLB Game

Best Bets: Cardinals vs. Cubs

• Run Line: Cardinals +1.5 @ -165 via DraftKings Sportsbook (63% probability)
• Moneyline: Cardinals @ +120 via DraftKings Sportsbook
• Total: Under 8.5 @ -115 via BetMGM (55% probability)

Dimers' best bets are based on detailed simulations and gambling expertise to help you make more informed investments with the legal sportsbooks in America.

While the Cubs are more likely to win the game, according to DimersBOT, taking the Cardinals moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers.com is pivotal to achieving long-term profitability as a sports bettor.

Cardinals vs. Cubs Prediction

Dimers.com predicts that the Cubs are more likely to beat the Cardinals at Wrigley Field on Friday.

This prediction is based on comprehensive data-driven analysis, with the Cubs given a 56% probability of winning after conducting 10,000 game simulations.

Click or tap on See Matchup to find out more.

Dimers has full betting coverage of Friday's Cardinals-Cubs game, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this article for the latest betting analysis before Cardinals vs. Cubs on Friday July 21, 2023.

Cardinals vs. Cubs 2023

Friday's MLB matchup between the Cubs and Cardinals at Wrigley Field is scheduled to start at 2:20PM ET.

• Who: St. Louis Cardinals vs. Chicago Cubs
• Date: Friday July 21, 2023
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

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Calling Our Shot ⚾️ Free Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

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Our picks and predictions are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Cardinals vs. Cubs picks can help you make informed decisions, it's crucial that you gamble responsibly and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What Other MLB Games Are on Today?

Now you've got the 411 on Cardinals vs. Cubs, check out the latest analysis for all upcoming MLB games via our MLB picks and predictions. There you can find probabilities and odds, and our best bets for each and every MLB matchup. Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good!

In addition to our leading MLB predictions, Dimers also offers the best MLB prop bets today, projecting home runs, RBIs, and more against the top odds available every single day of the MLB season.

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the World Series, with our data-driven probabilities compared to the best odds available.