Cardinals vs. Cubs Prediction and Odds - Aug 25, 2022

MLB action continues on Thursday at 2:20PM ET as the St. Louis Cardinals square off with the Chicago Cubs at Wrigley Field.

Marcus Stroman (3-5, 3.83 ERA) will be on the bump for the Cubs, up against Dakota Hudson (6-6, 4.33 ERA) for the Cardinals.

Dimers' free betting picks for Cardinals vs. Cubs, plus game predictions and betting odds, are detailed below.

Who will win Cardinals vs. Cubs?

Based on advanced computer power and data, Dimers.com has simulated Thursday's Cardinals-Cubs MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Cardinals a 53% chance of defeating the Cubs.

More: Cardinals vs. Cubs Simulated 10K Times

Cardinals vs. Cubs Odds

• Run Line: Cubs +1.5 (-165), Cardinals -1.5 (+150)
• Moneyline: Cubs -110, Cardinals -102
• Total: Over/Under 10 (-114/+100)

Run Line, Moneyline and Over/Under

The Cubs are listed as +1.5 underdogs versus the Cardinals, with -165 at BetMGM the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +150.

In a sign of how close this game is expected to be, both the Cubs and Cardinals are currently at minus-money betting odds to win on Thursday.

BetMGM currently has the best moneyline odds for the Cubs at -110, which means you can risk $110 to win $100, for a total payout of $210, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at -102, where you can risk $102 to win $100, for a total payout of $202, if they come out on top.

The Over/Under sits at 10 with FanDuel Sportsbook, which currently has the best odds for the Over at -114, while DraftKings Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 59% chance of covering the run line, while the 10-run Over/Under is a 53% chance of going Under.

More: Best Prop Bets to Make Today

Best Bets for Cardinals vs. Cubs

• Run Line: Cardinals -1.5 @ +150 via DraftKings Sportsbook (0.8% edge)
• Moneyline: Cardinals @ -102 via FanDuel Sportsbook (53% probability)
• Total: Under 10 @ +100 via DraftKings Sportsbook (53% probability)

Dimers' best bets are based on world-class modeling and wagering expertise to help you make more informed investments with the legal sportsbooks in the United States.

Although the Cubs are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

Cardinals vs. Cubs Prediction

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for St. Louis vs. CHI Cubs, and click or tap on See Matchup for more.

Dimers has full coverage of Thursday's Cardinals-Cubs matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates often, so check this article for any changes to our betting analysis before Cardinals vs. Cubs on Thursday August 25, 2022.

Cardinals vs. Cubs 2022 Game Info

Thursday's matchup between the Cubs and Cardinals at Wrigley Field is scheduled to begin at 2:20PM ET.

• Who: St. Louis Cardinals vs. Chicago Cubs
• Date: Thursday August 25, 2022
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

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