Cardinals vs. Brewers Prediction and Odds - Sep 28, 2022

The Milwaukee Brewers and St. Louis Cardinals are scheduled to meet in MLB at American Family Field on Wednesday, starting at 7:40PM ET.

The Brewers will send Brandon Woodruff (12-4, 3.18 ERA) to the mound, up against José Quintana (6-6, 3.02 ERA) for the Cardinals.

Dimers' free betting picks for Cardinals vs. Brewers, as well as game predictions and betting odds, are featured below.

Who will win Cardinals vs. Brewers?

Using cutting-edge computer power and data, Dimers.com has simulated Wednesday's Cardinals-Brewers MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Brewers a 57% chance of beating the Cardinals.

More: Cardinals vs. Brewers Simulated 10K Times

Cardinals vs. Brewers Odds

• Run Line: Brewers -1.5 (+122), Cardinals +1.5 (-140)
• Moneyline: Brewers -175, Cardinals +160
• Total: Over/Under 7 (-108/-105)

Run Line, Moneyline and Over/Under

The Brewers are listed as -1.5 favorites against the Cardinals, with +122 at Caesars Sportsbook the best odds currently available.

For the underdog Cardinals (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -140.

BetMGM currently has the best moneyline odds for the Brewers at -175. That means you can risk $175 to win $100, for a total payout of $275, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at +160, where you can bet $100 to profit $160, earning a total payout of $260, if they win.

The Over/Under sits at 7 with FanDuel Sportsbook, which currently has the best odds for the Over at -108, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, check out all of the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 7 runs is a 58% chance of going Over.

More: Best Prop Bets Today

Best Bets for Cardinals vs. Brewers

• Run Line: Cardinals +1.5 @ -140 via DraftKings Sportsbook (61% probability)
• Moneyline: Cardinals @ +160 via FanDuel Sportsbook (4.7% edge) 🔥
• Total: Over 7 @ -108 via FanDuel Sportsbook (58% probability) 🔥

When you see a 🔥, that means you've found one of our best free picks today across all sports.

Dimers' best bets are based on complex modeling and gambling expertise to help you make better decisions with your state's legal sportsbooks.

While the Brewers are more likely to win the game, according to DimersBOT, betting on the Cardinals moneyline is the best option due to the 4.7% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers.com is one of the keys to being a profitable bettor in the long run.

Cardinals vs. Brewers Prediction

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Dimers has full coverage of Wednesday's Cardinals-Brewers matchup, including pregame predictions, computer picks, and live updates.

Remember, DimersBOT updates frequently, so refresh this article for any changes to our betting insights before Cardinals vs. Brewers on Wednesday September 28, 2022.

Cardinals vs. Brewers 2022 Game Info

Wednesday's game between the Brewers and Cardinals at American Family Field is scheduled to start at 7:40PM ET.

• Who: St. Louis Cardinals vs. Milwaukee Brewers
• Date: Wednesday September 28, 2022
• Time: 7:40PM ET / 4:40PM PT
• Venue: American Family Field

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What other MLB games are on today?

The Cardinals and Brewers aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single MLB game via our MLB Predictions section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.