Cardinals vs. 49ers Week 4 Prediction and Odds - October 1, 2023

NFL Week 4 action continues on Sunday at 4:25PM ET as the Arizona Cardinals look to defy the odds against the San Francisco 49ers at Levi's Stadium.

Dimers' free betting picks for Cardinals vs. 49ers, plus game predictions, betting odds and touchdown scorer probabilities, are featured below.

This Arizona vs. San Francisco betting analysis is sponsored by Bet365, which has an awesome Bet $1, Get $365 in Bonus Bets offer for new customers.

Who Will Win: Cardinals vs. 49ers

Using advanced computer power and data, Dimers.com has simulated Sunday's Cardinals-49ers NFL game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the 49ers a 90% chance of beating the Cardinals in Week 4 of the NFL season.

More: Cardinals vs. 49ers Simulated 10K Times

Cardinals vs. 49ers Odds

• Spread: 49ers -15 (-110), Cardinals +15 (-108)
• Moneyline: 49ers -1099, Cardinals +750
• Total: Over/Under 44 (-110/-105)

The 49ers are currently -15 favorites versus the Cardinals, with -110 at PointsBet the best odds currently available.

For the underdog Cardinals (+15) to cover the spread, DraftKings Sportsbook has the best odds currently on offer at -108.

PointsBet currently has the best moneyline odds for the 49ers at -1099. That means you can risk $1,099 to win $100, for a total payout of $1,199, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at +750, where you can put down $100 to profit $750, earning a total payout of $850, if they win.

The Over/Under for total points scored sits at 44 with PointsBet, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, check out all the online sportsbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the Cardinals (+15) have a 56% chance of covering the spread, while the Over/Under total of 44 points has a 56% chance of going Under.

More: Best Bets for Every NFL Game

Best Bets: Cardinals vs. 49ers

• Spread: Cardinals +15 @ -108 via DraftKings Sportsbook (56% probability) 🔥
• Moneyline: 49ers @ -1099 via PointsBet (90% probability)
• Total: Under 44 @ -105 via DraftKings Sportsbook (56% probability) 🔥

Every time you see a 🔥, you know it's one of our best free picks today across all sports.

Our best bets are based on detailed simulations and wagering intelligence to help you make smarter decisions with the legal sportsbooks in the United States.

Cardinals vs. 49ers Prediction

Dimers.com's predicted final score for Arizona vs. San Francisco at Levi's Stadium in Week 4 has the 49ers winning 28-15.

Click or tap on See Matchup for more information.

Dimers has full coverage of this week's Cardinals-49ers game in Week 4, including pregame predictions, free betting picks, and live win probabilities.

Cardinals vs. 49ers Player Props

Who will score an anytime touchdown in Cardinals vs. 49ers? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Cardinals and 49ers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you discover the best prop picks for Sunday's game.

According to DimersBOT, San Francisco's Christian McCaffrey is most likely to score the first TD in Cardinals vs. 49ers.

DimersBOT gives McCaffrey a 22.2% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 71.6% chance of scoring an anytime touchdown.

Scroll down for the full list of first and anytime TD scorer probabilities, which provide a great avenue for you to use this DraftKings Sportsbook offer, which unlocks $200 in bonus bets from a $5 bet on any of the below players.

First Touchdown Scorer Probabilities

Arizona Cardinals

• James Conner: 10.6% probability
• Marquise Brown: 5.5% probability
• Michael Wilson: 4.3% probability
• Zach Ertz: 3.5% probability
• Rondale Moore: 3.3% probability

San Francisco 49ers

• Christian McCaffrey: 22.2% probability
• Brandon Aiyuk: 9.9% probability
• George Kittle: 8.9% probability
• Deebo Samuel: 7.9% probability
• Jordan Mason: 5.0% probability

Anytime Touchdown Scorer Probabilities

Arizona Cardinals

• James Conner: 45.9% probability
• Marquise Brown: 25.7% probability
• Michael Wilson: 20.7% probability
• Rondale Moore: 17.2% probability
• Zach Ertz: 17.1% probability

San Francisco 49ers

• Christian McCaffrey: 71.6% probability
• Brandon Aiyuk: 40.6% probability
• George Kittle: 38.1% probability
• Deebo Samuel: 34.3% probability
• Jordan Mason: 22.9% probability

Cardinals-49ers Projected Player Stats

Of the starting quarterbacks, the Cardinals' Joshua Dobbs is projected to have a quiet game with 162 passing yards. The 49ers' Brock Purdy is expected to throw for 234 yards.

Cardinals Starting QB

• Joshua Dobbs: 162 projected yards

49ers Starting QB

• Brock Purdy: 234 projected yards

Cardinals Rushing

• James Conner: 72 projected yards
• Joshua Dobbs: 15 projected yards
• Keaontay Ingram: 11 projected yards

49ers Rushing

• Christian McCaffrey: 94 projected yards
• Jordan Mason: 33 projected yards
• Deebo Samuel: 11 projected yards

Cardinals Receiving

• Marquise Brown: 41 projected yards
• Rondale Moore: 29 projected yards
• Zach Ertz: 27 projected yards
• Michael Wilson: 22 projected yards
• Trey McBride: 16 projected yards

49ers Receiving

• Brandon Aiyuk: 63 projected yards
• George Kittle: 57 projected yards
• Deebo Samuel: 47 projected yards
• Christian McCaffrey: 34 projected yards
• Ronnie Bell: 22 projected yards

Remember, DimersBOT updates frequently, so refresh this page for the latest betting insights ahead of Cardinals vs. 49ers on Sunday October 1, 2023.

Cardinals vs. 49ers 2023

The NFL Week 4 action between the 49ers and Cardinals at Levi's Stadium is scheduled to begin at 4:25PM ET.

• Who: Arizona Cardinals vs. San Francisco 49ers
• Date: Sunday October 1, 2023
• Time: 4:25PM ET / 1:25PM PT
• Venue: Levi's Stadium

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Make Informed Sports Betting Decisions Today

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Cardinals vs. 49ers picks can help you make informed decisions, it's crucial that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What NFL Games Are on Today?

Now you've got the 411 on Cardinals vs. 49ers, see the latest coverage for all NFL games via our NFL picks and predictions. There you can find probabilities and odds, as well as our best bets for each and every NFL matchup. Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good!

In addition to our leading NFL predictions, Dimers also offers the best NFL prop bets today, projecting passing yards, touchdowns, and more against the top odds available every single day of the NFL season.