Cardinals vs. 49ers Week 18 Prediction and Odds - Jan 8, 2023

The San Francisco 49ers take on the Arizona Cardinals in NFL Week 18 action at Levi's Stadium on Sunday, starting at 4:25PM ET.

Dimers' free betting picks for Cardinals vs. 49ers, as well as our score prediction, betting odds and projected player stats, are featured below.

Who will win Cardinals vs. 49ers?

Based on advanced computer power and data, Dimers.com has simulated Sunday's Cardinals-49ers NFL matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the 49ers a 93% chance of winning against the Cardinals in Week 18 of the NFL season.

More: Cardinals vs. 49ers Simulated 10K Times

Cardinals vs. 49ers Week 18 Odds

• Spread: 49ers -14.5 (-105), Cardinals +14.5 (-110)
• Moneyline: 49ers -800, Cardinals +750
• Total: Over/Under 39.5 (-110/-110)

Point Spread, Moneyline and Over/Under

The 49ers are listed as -14.5 favorites against the Cardinals, with -105 at FanDuel Sportsbook the best odds currently available.

For the underdog Cardinals (+14.5) to cover the spread, Caesars Sportsbook has the best odds currently on offer at -110.

PointsBet currently has the best moneyline odds for the 49ers at -800. That means you can risk $800 to win $100, for a total payout of $900, if they get the W.

Meanwhile, BetMGM currently has the best moneyline odds for the Cardinals at +750, where you can bet $100 to profit $750, earning a total payout of $850, if they win.

The Over/Under is set at 39.5 with PointsBet, which currently has the best odds for the Over at -110, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best NFL odds and lines.

According to DimersBOT, the Cardinals (+14.5) are a 51% chance of covering the spread, while the 39.5-point Over/Under is a 51% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Cardinals vs. 49ers

• Spread: 49ers -14.5 @ -105 via FanDuel Sportsbook (50% probability)
• Moneyline: 49ers @ -800 via PointsBet (93% probability) 🔥
• Total: Over 39.5 @ -110 via PointsBet (51% probability)

Every time you see a 🔥, that means it's one of our best free picks today across all major pro and college sports.

Dimers' best bets are based on complex modeling and wagering intelligence to help you make more informed decisions with your state's legal sportsbooks.

Even though the Cardinals are more likely to cover the spread, our best bet of 49ers -14.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Cardinals vs. 49ers Prediction

Dimers.com's predicted final score for Arizona vs. San Francisco at Levi's Stadium in Week 18 has the 49ers prevailing 27-12.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Cardinals-49ers matchup in Week 18, including pregame predictions, free picks, and live win probabilities.

Cardinals vs. 49ers Player Props

Who will score an anytime touchdown in Cardinals vs. 49ers? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Cardinals and 49ers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop picks for Sunday's game.

According to DimersBOT, San Francisco's Christian McCaffrey is most likely to score the first TD in Cardinals vs. 49ers.

DimersBOT gives McCaffrey a 17.8% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 59.8% chance of scoring an anytime touchdown.

Scroll down for the complete list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Arizona Cardinals

• Corey Clement: 7.1% probability
• Marquise Brown: 7.1% probability
• Trey McBride: 5.8% probability
• Keaontay Ingram: 5.3% probability
• Greg Dortch: 4.6% probability

San Francisco 49ers

• Christian McCaffrey: 17.8% probability
• George Kittle: 8.9% probability
• Brandon Aiyuk: 7.8% probability
• Deebo Samuel: 7.1% probability
• Jauan Jennings: 6.1% probability

Anytime Touchdown Scorer Probabilities

Arizona Cardinals

• Corey Clement: 32.4% probability
• Marquise Brown: 30.8% probability
• Trey McBride: 25.8% probability
• Keaontay Ingram: 25.0% probability
• Greg Dortch: 21.0% probability

San Francisco 49ers

• Christian McCaffrey: 59.8% probability
• George Kittle: 35.3% probability
• Brandon Aiyuk: 32.3% probability
• Deebo Samuel: 29.7% probability
• Jauan Jennings: 25.7% probability

Cardinals-49ers Projected Player Stats

Of the starting quarterbacks, the Cardinals' David Blough is projected for 191 passing yards, while the 49ers' Brock Purdy is expected to throw for 194 yards.

Cardinals Starting QB

• David Blough: 191 projected yards

49ers Starting QB

• Brock Purdy: 194 projected yards

Cardinals Rushing

• Corey Clement: 52 projected yards
• Keaontay Ingram: 29 projected yards
• David Blough: 11 projected yards

49ers Rushing

• Christian McCaffrey: 77 projected yards
• Elijah Mitchell: 30 projected yards
• Deebo Samuel: 17 projected yards

Cardinals Receiving

• Greg Dortch: 54 projected yards
• Marquise Brown: 47 projected yards
• Trey McBride: 43 projected yards
• Corey Clement: 29 projected yards
• Stephen Anderson: 14 projected yards

49ers Receiving

• Brandon Aiyuk: 67 projected yards
• George Kittle: 48 projected yards
• Christian McCaffrey: 42 projected yards
• Deebo Samuel: 41 projected yards
• Jauan Jennings: 33 projected yards

Don't forget, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis ahead of Cardinals vs. 49ers on Sunday January 8, 2023.

Cardinals vs. 49ers 2023

The NFL Week 18 matchup between the 49ers and Cardinals at Levi's Stadium is scheduled to begin at 4:25PM ET.

• Who: Arizona Cardinals vs. San Francisco 49ers
• Date: Sunday January 8, 2023
• Time: 4:25PM ET / 1:25PM PT
• Venue: Levi's Stadium

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