Buffalo vs. Louisiana-Lafayette CFB Prediction and Odds - September 23, 2023

Louisiana-Lafayette faces Buffalo in College Football action at Cajun Field on Saturday, starting at 7:30PM ET.

Dimers' best betting picks for Buffalo vs. Louisiana-Lafayette, as well as our score prediction and best odds, are detailed in this article.

Today's Buffalo vs. Louisiana-Lafayette betting preview is proudly sponsored by Bet365, which has a Bet $1, Get $365 in Bonus Bets promo for new users.

Who Will Win: Buffalo vs. Louisiana-Lafayette

Using trusted machine learning and data, Dimers.com has simulated Buffalo vs. Louisiana-Lafayette 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives Louisiana-Lafayette a 68% chance of winning against Buffalo.

More: Betting Picks for Buffalo vs. Louisiana-Lafayette

Buffalo vs. Louisiana-Lafayette Odds

• Spread: Louisiana-Lafayette -10.5 (-104), Buffalo +10.5 (-110)
• Moneyline: Louisiana-Lafayette -375, Buffalo +315
• Total: Over/Under 57.5 (-110/-110)

Louisiana-Lafayette is the -10.5 favorite against Buffalo, with -104 at FanDuel Sportsbook the best odds currently available.

For the underdog Buffalo (+10.5) to cover the spread, PointsBet has the best odds currently on offer at -110.

DraftKings Sportsbook currently has the best moneyline odds for Louisiana-Lafayette at -375, which means you can risk $375 to win $100, for a total payout of $475, if it gets the W.

Meanwhile, PointsBet currently has the best moneyline odds for Buffalo at +315, where you can bet $100 to profit $315, earning a total payout of $415, if it wins.

The Over/Under is set at 57.5 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all of the legal sportbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Buffalo (+10.5) has a 56% chance of covering the spread, while the 57.5-point Over/Under has a 51% chance of going Under.

More: Live Win Probabilities for All Major College Sports

Best Bets: Buffalo vs. Louisiana-Lafayette

• Spread: Buffalo +10.5 @ -110 via PointsBet (56% probability)
• Moneyline: Buffalo @ +315 via PointsBet (7.7% edge) 🔥
• Total: Under 57.5 @ -110 via PointsBet (51% probability)

When you see a 🔥, that means it's one of Dimers' best free picks today across all sports.

Our best bets are based on world-class simulations and betting intelligence to bring you the best possible plays every day of the year.

While Louisiana-Lafayette is more likely to win the game, according to DimersBOT, betting on Buffalo moneyline is the best option because of the 7.7% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen here at Dimers.com is pivotal to being profitable in the long run.

Buffalo vs. Louisiana-Lafayette Prediction

Dimers.com's predicted final score for Buffalo vs. Louisiana-Lafayette at Cajun Field this Saturday has Louisiana-Lafayette prevailing 32-24.

Click or tap on See Matchup for more information.

Dimers has full betting coverage of this week's Buffalo-Louisiana-Lafayette game, including pregame predictions, free picks, and live updates.

Don't forget, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis before Buffalo vs. Louisiana-Lafayette on Saturday September 23, 2023.

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Buffalo vs. Louisiana-Lafayette 2023

Saturday's game between Louisiana-Lafayette and Buffalo in College Football at Cajun Field is scheduled to begin at 7:30PM ET.

• Who: Buffalo vs. Louisiana-Lafayette
• Date: Saturday September 23, 2023
• Time: 7:30PM ET / 4:30PM PT
• Venue: Cajun Field

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Make Smarter Sports Betting Decisions Today

Dimers' picks and predictions are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Buffalo vs. Louisiana-Lafayette predictions can help you make informed decisions, it's vital that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More CFB Analysis Like This?

So, you liked our Buffalo vs. Louisiana-Lafayette betting analysis? Awesome. Did you know our College Football Betting News page has a comprehensive betting preview for every CFB game the second the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets, which allows us to produce the most authoritative CFB betting previews and get the jump on the public and the sportsbooks.

In addition to our leading CFB predictions, we also feature the best CFB prop bets today, projecting passing yards, touchdowns, and more against the best odds available every day of the CFB season.