Bills vs. Lions Prediction: Detroit Predicted to Win in NFL Week 15 [2024]

The Detroit Lions and Buffalo Bills are scheduled to meet in Week 15 of the NFL season at Ford Field on Sunday, starting at 4:25PM ET.

Based on the latest simulations, Dimers' proven NFL model (see Dimers Pro for full access) predicts the Lions as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Buffalo-Detroit game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Lions with a win probability of 60%, while the Bills have 40%."

This updated Bills vs. Lions betting preview builds on my early Bills vs. Lions prediction that I published at the start of the week.

For a closer look at today’s game, including the predicted score, best bets and player prop picks, visit our interactive Bills vs. Lions predictions page.

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Bills vs. Lions Game-Day Updates and Essential Details

The NFL Week 15 game between the Lions and Bills at Ford Field is scheduled to start at 4:25PM ET.

• Who: Buffalo Bills vs. Detroit Lions
• Date: Sunday, December 15, 2024
• Time: 4:25PM ET/1:25PM PT
• Venue: Ford Field
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Lions and Bills gear at Fanatics

Dimers.com's full preview of this week's Bills vs. Lions matchup includes our prediction, picks and the latest betting odds.

Before making any Buffalo vs. Detroit picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

Bills vs. Lions Predictions

Using powerful machine learning and data, we have simulated the outcome of Sunday's NFL game between the Bills and Lions 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the Lions a 60% chance of defeating the Bills in Week 15 of the NFL season. Our predicted final score has the Lions winning 28-25.

According to our model, the bookmakers have got it right, and the Bills and Lions each have a 50% chance of covering the spread, while the over/under total of 54.5 points also has an equal 50-50 chance of hitting.

Bills vs. Lions Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	Bills	Lions
Spread	+2.5 (+100)	-2.5 (-110)
Moneyline	+124	-144
Total	o54.5 (-110)	u54.5 (-110)

All odds are correct at the time of publication and are subject to change.

Bills vs. Lions Picks

Our model's biggest edge in today's Bills vs. Lions matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Bills vs. Lions TD Scorers

Who will score the first touchdown in Bills vs. Lions?

According to our model, Detroit's David Montgomery is most likely to score the first touchdown in Bills vs. Lions.

Our projections give Montgomery a 12.6% chance of scoring the first TD at Ford Field, while the Lions RB is a 57.8% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

Buffalo Bills

Player	First TD Probability
Josh Allen	8.7%
James Cook	8.4%
Amari Cooper	5.2%

Detroit Lions

Player	First TD Probability
David Montgomery	12.6%
Jahmyr Gibbs	11.1%
Amon-Ra St. Brown	8.4%

Anytime Touchdown Scorer Predictions

Buffalo Bills

Player	Anytime TD Probability
Josh Allen	42.8%
James Cook	41.5%
Amari Cooper	29.4%

Detroit Lions

Player	Anytime TD Probability
David Montgomery	57.8%
Jahmyr Gibbs	52.2%
Amon-Ra St. Brown	41.5%

Bills vs Lions Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Bills and Lions. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Bills-Lions page now to access every player prop projection.

Bills vs. Lions Quarterbacks

Of the starting quarterbacks, the Bills' Josh Allen is projected to throw for more yards than the Lions' Jared Goff.

Bills Rushing

James Cook, Josh Allen and Ray Davis are projected to be the leading rushers for the Bills.

Player	Position
James Cook	RB
Josh Allen	QB
Ray Davis	RB

Lions Rushing

Jahmyr Gibbs, David Montgomery and Jared Goff are expected to lead the Lions in rushing yards.

Player	Position
Jahmyr Gibbs	RB
David Montgomery	RB
Jared Goff	QB

Bills Receiving

Khalil Shakir, Amari Cooper, Dalton Kincaid, Keon Coleman and Mack Hollins are projected to top the receiving yards for the Bills.

Player	Position
Khalil Shakir	WR
Amari Cooper	WR
Dalton Kincaid	TE
Keon Coleman	WR
Mack Hollins	WR

Lions Receiving

Amon-Ra St. Brown, Jameson Williams, Sam LaPorta, Tim Patrick and Jahmyr Gibbs are projected to lead the Lions in receiving yards.

Player	Position
Amon-Ra St. Brown	WR
Jameson Williams	WR
Sam LaPorta	TE
Tim Patrick	WR
Jahmyr Gibbs	RB

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Conclusion

We predict the Lions, with a 60% win probability, will likely beat the Bills in Week 15 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Bills vs. Lions insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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