St Kilda Saints vs. Brisbane Lions Prediction: Lions Predicted to Win Friday's AFL Round 7 Matchup [4/25/2025]

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Written by Damien Souness

Our expert prediction for Friday's St Kilda Saints vs Brisbane Lions matchup.

St Kilda Saints-Brisbane Lions Predictions and Game Preview.
Marvel Stadium sets the stage for the AFL matchup between the St Kilda Saints and Brisbane Lions this Friday.

AFL action continues on Friday at 11:20PM ET as the favored Brisbane Lions square off with the St Kilda Saints at Marvel Stadium.

Based on the latest simulations, Dimers' advanced AFL model (see Dimers Pro for full access) predicts the Lions as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Brisbane-St Kilda game 10,000 times," said Ryan Leaver from Dimers.

"After computing the latest updates and thousands of other inputs, we predict the Lions' chance of winning is 66%, while the Saints' is 34%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Lions vs. Saints predictions page.

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Saints vs. Lions Prediction: Who Will Win Round 7 Game?

Using powerful machine learning and statistical analysis, we have simulated the result of Friday's AFL matchup between the Lions and Saints 10,000 times as part of our AFL predictions coverage.

Our independent predictive model gives the Lions a 66% chance of defeating the Saints.

According to our model, the Saints (+14.5) have a 55% chance of covering the spread, while the over/under total of 179.5 has a 53% chance of staying under.

Pre-Game Probabilities
Last Updated: 10:31AM, Apr 25
Moneyline
Spread
Over / Under
Lions
Win %
66%
34%
Get the best bets with Dimers Pro
See Matchup
Saints
Lions BRI
Win %
66%
34%
See Matchup
Saints STK
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Brisbane vs. St Kilda Odds

We have researched the best AFL odds in America for this game, which are listed here:

Bet Type Lions Saints
H2H (Moneyline) -233 +170
Line (Spread) -14.5 (-115) +14.5 (-115)
Total o179.5 (-120) u179.5 (-120)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Saints vs. Lions Game-Day Updates and Essential Details

Friday's Australian rules football matchup between the Saints and Lions at Marvel Stadium is scheduled to commence at 11:20PM ET.

  • Who: Brisbane Lions vs. St Kilda Saints
  • Date: Friday, April 25, 2025
  • Time: 11:20PM ET/8:20PM PT
  • Venue: Marvel Stadium

The AFL is available to bet on in the US through all major sportsbooks, with fans highlighting the high-octane 360-degree nature of the sport as a top reason to follow it.

Dimers.com's full preview of Friday's Lions vs. Saints matchup includes our prediction, picks and the latest betting odds.

Before making any Brisbane vs. St Kilda picks, be sure to check out the latest AFL predictions and betting advice from Dimers Pro.

Conclusion

We predict the Lions, with a 66% win probability, will likely beat the Saints on Friday.

AI and automation have enhanced this article to quickly deliver accurate Lions vs. Saints insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on AFL

Keep up with the latest AFL news and parlay picks throughout the season.

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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