Red Sox vs. White Sox Prediction: Boston Predicted to Win Saturday's MLB Matchup [4/12/2025]

The Chicago White Sox will square off with the Boston Red Sox in MLB action at Rate Field on Saturday, commencing at 4:10PM ET.

Martín Pérez (1-0, 0.73 ERA) will start on the mound for the White Sox, while the Red Sox have opted for Richard Fitts (0-2, 4.50 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Red Sox as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Boston-CHI White Sox game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Red Sox are more likely to win, while the White Sox have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Red Sox vs. White Sox predictions page.

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Red Sox vs. Red Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Saturday's MLB game between the Red Sox and White Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Red Sox a 56% chance of beating the White Sox.

According to our model, the White Sox (+1.5) have a 58% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of going over.

Pre-Game Probabilities

Last Updated: 8:28PM, Apr 12

Moneyline

Over / Under

Run Line

Red Sox

Win %

56%

44%

-157

+136

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White Sox

Red Sox BOS

-157

Win %

56%

44%

See Matchup

White Sox CWS

+136

Richard Fitts 0-2, 4.50 ERA

Martín Pérez 1-0, 0.73 ERA

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Red Sox vs. White Sox Odds [4/12/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Red Sox vs. White Sox Picks and Best Bets

Our model's biggest edge in today's Red Sox vs. White Sox matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Red Sox vs. White Sox Game-Day Updates and Essential Details

Saturday's MLB action between the White Sox and Red Sox at Rate Field is scheduled to commence at 4:10PM ET.

• Who: Boston Red Sox vs. Chicago White Sox
• Date: Saturday, April 12, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Rate Field

Dimers.com's comprehensive preview of Saturday's Red Sox vs. White Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Boston vs. CHI White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Red Sox, with a 56% win probability, will likely beat the White Sox on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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