Celtics vs. Pistons Prediction: Boston Predicted to Win Wednesday's NBA Matchup [2/26/2025]

The Detroit Pistons and Boston Celtics will meet in NBA action at Little Caesars Arena on Wednesday, with tipoff at 7:00PM ET.

Based on updated simulation results and today’s injury updates, Dimers' advanced NBA model (see Dimers Pro for full access) predicts the Celtics as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Boston-Detroit game 10,000 times," said Damien Souness from Dimers.

"With the latest updates and numerous other variables, we estimate the Celtics' chance of winning at 66%, with the Pistons at 34%."

This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature stars like Cade Cunningham, Malik Beasley and Tobias Harris, while the Celtics will be led by Jayson Tatum, Kristaps Porzingis and Derrick White.

For a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Celtics vs. Pistons predictions page.

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Pistons vs. Celtics Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's NBA game between the Celtics and Pistons 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the Celtics a 66% chance of defeating the Pistons. Our predicted final score has the Celtics winning 114-109.

According to our model, the Celtics (-5) have a 51% chance of covering the spread, while the over/under total of 224.5 points has an equal 50-50 chance of hitting.

Celtics vs. Pistons Odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Celtics	Pistons
Spread	-5 (-108)	+5 (-112)
Moneyline	-198	+166
Total	o224.5 (-112)	u224.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Celtics vs. Pistons Picks and Best Bets

Our model's biggest edge in today's Celtics vs. Pistons matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best NBA picks for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Celtics vs. Pistons Player Props

Betting on Boston vs. Detroit NBA player props? We use the best information available to project how each team's leading players will perform at Little Caesars Arena.

Jayson Tatum is expected to lead the Celtics in scoring, while Cade Cunningham is projected to be the top scorer for the Pistons.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Calling Our Shot's Free NBA Picks

Calling Our Shot produces daily NBA betting content, including the best bets featured below.

Celtics vs. Pistons Game-Day Updates and Essential Details

Wednesday's action between the Pistons and Celtics at Little Caesars Arena is scheduled to begin at 7:00PM ET.

• Who: Boston Celtics vs. Detroit Pistons
• Date: Wednesday, February 26, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Little Caesars Arena

Dimers.com's full preview of Wednesday's Celtics vs. Pistons matchup includes our prediction, picks and the latest betting odds.

Before making any Boston vs. Detroit picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Celtics, with a 66% win probability, will likely beat the Pistons on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Celtics vs. Pistons insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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