Bills vs. Chiefs Week 6 Prediction and Odds - Oct 16, 2022

The Kansas City Chiefs and Buffalo Bills clash in Week 6 of the NFL season at GEHA Field at Arrowhead Stadium on Sunday, starting at 4:25PM ET.

Dimers' top betting picks for Bills vs. Chiefs, as well as game predictions, betting odds and touchdown scorer probabilities, are detailed in this article.

Who will win Bills vs. Chiefs?

Using advanced machine learning and data, Dimers.com has simulated Sunday's Bills-Chiefs NFL game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Bills a 55% chance of defeating the Chiefs in Week 6 of the NFL season.

More: Full Betting Analysis for Bills vs. Chiefs

Bills vs. Chiefs Odds

• Spread: Chiefs +2.5 (-104), Bills -2.5 (-107)
• Moneyline: Chiefs +124, Bills -135
• Total: Over/Under 53.5 (-115/-105)

Point Spread, Moneyline and Over/Under

The Chiefs are currently +2.5 underdogs versus the Bills, with -104 at FanDuel Sportsbook the best odds currently available.

For the favored Bills (-2.5) to cover the spread, PointsBet has the best odds currently on offer at -107.

FanDuel Sportsbook currently has the best moneyline odds for the Chiefs at +124. That means you can throw down $100 to profit $124, earning a total payout of $224, if they win.

Elsewhere, PointsBet currently has the best moneyline odds for the Bills at -135, where you can risk $135 to win $100, for a total payout of $235, if they come out on top.

The Over/Under sits at 53.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best NFL odds and lines.

According to DimersBOT, the Chiefs (+2.5) are a 60% chance of covering the spread, while the Over/Under total of 53.5 points is a 52% chance of going Under.

More: Free Prop Picks

Best Bets for Bills vs. Chiefs

• Spread: Chiefs +2.5 @ -104 via FanDuel Sportsbook (60% probability) 🔥
• Moneyline: Chiefs @ +124 via FanDuel Sportsbook (1.4% edge)
• Total: Under 53.5 @ -105 via FanDuel Sportsbook (52% probability)

If you see a 🔥, you know it's one of Dimers' best bets today across all major pro and college sports.

Dimers' best bets are based on complex modeling and betting intelligence to serve you the best possible plays 24/7/365.

While the Bills are more likely to win the game, according to DimersBOT, betting on the Chiefs moneyline is the best option due to the 1.4% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers.com is pivotal to being a profitable sports bettor in the long run.

Bills vs. Chiefs Prediction

Dimers.com's predicted final score for Buffalo vs. Kansas City at GEHA Field at Arrowhead Stadium in Week 6 has the Bills winning 27-26.

Click or tap on See Matchup for more.

Dimers has full coverage of this week's Bills-Chiefs matchup in Week 6, including pregame predictions, free picks, and live win probabilities.

Bills vs. Chiefs Player Props

Who will score the first touchdown in Bills vs. Chiefs? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Bills and Chiefs, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop picks for Sunday's game.

According to DimersBOT, Buffalo's Stefon Diggs is most likely to score the first TD in Bills vs. Chiefs.

DimersBOT gives Diggs a 10.9% chance of scoring the first TD at GEHA Field at Arrowhead Stadium, while the Bills WR is a 50.9% chance of reaching the end zone at any point in the game.

Scroll down for our complete list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Buffalo Bills

• Stefon Diggs: 10.9% probability
• Gabe Davis: 7.6% probability
• Josh Allen: 7.4% probability
• Devin Singletary: 5.4% probability
• Zack Moss: 5.2% probability

Kansas City Chiefs

• Travis Kelce: 8.8% probability
• Clyde Edwards-Helaire: 7.2% probability
• Marquez Valdes-Scantling: 6.9% probability
• Mecole Hardman: 5.8% probability
• JuJu Smith-Schuster: 5.6% probability

Anytime Touchdown Scorer Probabilities

Buffalo Bills

• Stefon Diggs: 50.9% probability
• Gabe Davis: 39.7% probability
• Josh Allen: 38.6% probability
• Zack Moss: 29.1% probability
• Devin Singletary: 29.1% probability

Kansas City Chiefs

• Travis Kelce: 43.4% probability
• Clyde Edwards-Helaire: 36.2% probability
• Marquez Valdes-Scantling: 36.0% probability
• Mecole Hardman: 31.0% probability
• JuJu Smith-Schuster: 29.8% probability

Bills-Chiefs Projected Player Stats

Of the starting quarterbacks, the Bills' Josh Allen is projected to have a big game with 299 passing yards. The Chiefs' Patrick Mahomes is expected to throw for a whopping 286 yards.

Bills Starting QB

• Josh Allen: 299 projected yards

Chiefs Starting QB

• Patrick Mahomes: 286 projected yards

Bills Rushing

• Josh Allen: 50 projected yards
• Devin Singletary: 43 projected yards
• Zack Moss: 17 projected yards

Chiefs Rushing

• Clyde Edwards-Helaire: 38 projected yards
• Patrick Mahomes: 22 projected yards
• Isiah Pacheco: 21 projected yards

Bills Receiving

• Stefon Diggs: 88 projected yards
• Gabe Davis: 77 projected yards
• Isaiah McKenzie: 31 projected yards
• Dawson Knox: 24 projected yards
• Devin Singletary: 21 projected yards

Chiefs Receiving

• Travis Kelce: 84 projected yards
• JuJu Smith-Schuster: 54 projected yards
• Mecole Hardman: 41 projected yards
• Marquez Valdes-Scantling: 40 projected yards
• Clyde Edwards-Helaire: 21 projected yards

Don't forget, DimersBOT updates frequently, so check this page for any changes to our betting analysis ahead of Bills vs. Chiefs on Sunday October 16, 2022.

Bills vs. Chiefs 2022

The NFL Week 6 game between the Chiefs and Bills at GEHA Field at Arrowhead Stadium is scheduled to begin at 4:25PM ET.

• Who: Buffalo Bills vs. Kansas City Chiefs
• Date: Sunday October 16, 2022
• Time: 4:25PM ET / 1:25PM PT
• Venue: GEHA Field at Arrowhead Stadium

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