MLS Best Bets: Soccer Picks & Parlay for Saturday, February 25

Major League Soccer (MLS) is back with a bang for Matchweek 1 this weekend, in a season that is highly anticipated. We're getting ready for a big opening slate of games by taking a look at the MLS Best Bets for Week 1, sourced from our DimersBOT MLS predictions model, which simulates every game to determine the best soccer bets. This week's article features Nashville vs. New York City, Philadelphia vs. Columbus and Austin vs. St Louis City, all taking place on Saturday, February 25, 2023. Read on for our full analysis below. 

RELATED: Check out our favorite MLS Best Bets for every game.

If you haven't already, you should consider signing up for DraftKings ➡️ here ⬅️ as you can turn a $5 pre-game moneyline bet on any game into $150 in free bonus bets if your team wins. Need a can't-miss favorite to bet on to ensure you get the bonus? Our MLS Best Bets is the perfect resource to find the best pick of the weekend.

MLS Best Bets for Week 1

Nashville SC vs. New York City

The MLS season gets underway at GEODIS Park in Nashville when they host New York City in a game that our model is siding with the home team on. Nashville head into the game as favorites on the moneyline, listed with the 'books at +110. Our MLS data model gives them a 51% chance to win, giving us a significant plus money edge.

BET: Nashville ML (+110) with DraftKings ➡️ here ⬅️.

⚽️ Nashville vs. New York City Predictions
💰 Full Preview: Nashville vs. NY City

Philadelphia Union vs. Columbus Crew

Last year's Eastern Conference champions, Philadelphia will open up their 2023 campaign against Columbus in a game that the Union will be hungry to win after the disappointment of losing the MLS Cup to LAFC last season. Philly are set to be strong again this season, listed second in betting for this year's MLS Cup at odds of +600. They should make light work of the middling Columbus, with our projections giving the Union a 65.1% chance of victory.

BET: Philadelphia ML (-145) with DraftKings ➡️ here ⬅️.

⚽️ Philadelphia vs. Columbus Predictions
💰 Full Preview: Philadelphia vs. Columbus

Austin FC vs. St. Louis City

Expectations are high in Texas for Austin to continue their ascent to one of the powerhouses of the MLS. As we outlined in our MLS Futures piece, Austin are one of our top picks to take home the MLS Cup, and will enter the season boasting one of the most potent attacks in the league with Sebastian Driussi, Gyasi Zardes and Emiliano Rigoni. They open up their season against new boys St Louis City, and our model is all over this one being a goalfest, picking the Over 2.5 Goals market with a 64.6% chance of hitting.

BET: Over 2.5 Goals (-128) with DraftKings ➡️ here ⬅️.

⚽️ Austin FC vs. St. Louis City Predictions
💰 Full Preview: Austin FC vs. St. Louis City

Your game not here? Find out who we're betting on for every MLS game this weekend via our MLS Bet Hub, where we deliver you soccer predictions and suggested bets, or check out the MLS Betting News section.

Best MLS Parlay for Matchweek 1

There are numerous different ways you can wager on MLS games in 2023, such as the moneyline, total goals, player and team props, and, of course, parlays. While we normally suggest taking our picks on their own, we love parlays too! With that said, check out the fat payout you can get by throwing all of our best bets together tonight. Also, feel free to make your own parlays using our MLS Parlay tool! 

🔥 Nashville ML
🔥 Philadelphia ML
🔥 Austin/St Louis Over 2.5 Goals

Want more parlays? Head to our NEW MLS Parlay Picker where we use the power of our artificial intelligence to generate the best parlays for you across all the pro and college sports in the United States.

*All odds and lines correct at time of publishing