Best College Football Betting Picks, Predictions and Parlays: Week 2, Saturday September 11, 2021

Week 1 was one for the ages and now we've got a whole new slate of College Ball to look forward to as we zone in on some of our best picks provided by our data projection model.

It's Saturday September 11, 2021, and, as always, we've simulated all of the day's College Football games 10,000 times each to determine where the value lies for baseball bettors across the United States.

With College Football betting picks, probabilities, odds and predicted scores featured each and every day, check out our top plays for Saturday's College Football games by reading this article.

Today's College Football best bets and odds are proudly brought to you by PointsBet Sportsbook.

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Free CFB Picks For Saturday September 11, 2021

Oregon vs. Ohio State

BET: Total points OVER 63.5 with PointsBet (-108)

📈 52% probability

Both programs got their seasons off to winning starts last week, but it's the powerhouses Ohio State who are favored overwhelmingly today. Apart from just winning last week, both teams have some shoddy Week 1 defense in common, each conceding multiple touchdowns. The total is set high here but our projections have it sailing over.

MORE: Oregon vs. Ohio State predictions and picks

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Eastern Michigan vs. Wisconsin

BET: Total points UNDER 52 with PointsBet (-105)

📈 58.2% probability

With Wisconsin heavily favored at the spread here, our data is predicting more of the same stifling defense that was a feature of their season opener last week against Penn State. The Badgers couldn't get the win, due to some struggles on offense, but they'll buoyed by the fact that they were able to keep the Nittany Lions down to only 16 points. Coming up against an inferior opponent in Eastern Michigan should allow them to continue to restrict on defense.

MORE: Eastern Michigan vs. Wisconsin predictions and picks

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Toledo vs. Notre Dame

BET: Notre Dame -17 with PointsBet (+100)

📈 3.2% edge on the sportsbooks' odds

Notre Dame played in an early contender for game of the year on Monday night when they scraped by FSU in OT, but we're not expecting the same sort of trouble - or a cameo from McKenzie Milton - in this one when the Fighting Irish take on Toledo. The Rockets had a healthy win to start their year off against Norfolk State, but we're talking about a contender here. Notre Dame took their foot off the pedal on Monday and we're expecting a large overcorrection in what will be a dominant display.

MORE: Toledo vs. Notre Dame predictions and picks

Your game not here? Find out who we're betting on for every College game on Saturday via our College Football Bet Hub, where we deliver you CFB predictions and suggested bets.

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College Football Parlay For Saturday September 11, 2021

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🔥 Oregon/Ohio State o63.5
🔥 East Mich/Wisconsin u52
🔥 Notre Dame ATS

Parlay Odds +652

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SATURDAY CFB HUB:

🏈 PROSPECTOR SAM'S WEEK 2 CFB PICKS
🏈 #10 IOWA VS. IOWA STATE PREVIEW
🏈 PROJECTIONS FOR EVERY GAME

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