Orioles vs. Diamondbacks Prediction: Arizona Predicted to Win Wednesday's MLB Matchup [4/9/2025]

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Written by Dave Garofolo

Our expert prediction for Wednesday's Baltimore Orioles vs Arizona Diamondbacks matchup.

Baltimore Orioles-Arizona Diamondbacks Predictions and Game Preview.
Chase Field sets the stage for the MLB matchup between the Baltimore Orioles and Arizona Diamondbacks this Wednesday.

MLB action continues on Wednesday at 3:40PM ET as the Baltimore Orioles lock horns with the Arizona Diamondbacks at Chase Field.

Brandon Pfaadt (1-1, 5.25 ERA) will get the ball for the Diamondbacks, up against Dean Kremer (1-1, 6.52 ERA) for the Orioles.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Baltimore-Arizona game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Diamondbacks' chance of winning at 52%, with the Orioles at 48%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Orioles vs. Diamondbacks predictions page.

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Orioles vs. Orioles Prediction: Who Will Win?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Orioles and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Diamondbacks a 52% chance of defeating the Orioles.

According to our model, the 9-run over/under also has an equal 50-50 chance of hitting.

Pre-Game Probabilities
Last Updated: 7:28PM, Apr 9
Moneyline
Over / Under
Run Line
Orioles
Win %
48%
52%
Get the best bets with Dimers Pro
See Matchup
D-Backs
Orioles BAL
Win %
48%
52%
See Matchup
D-Backs ARI
Dean Kremer 1-1, 6.52 ERA
Brandon Pfaadt 1-1, 5.25 ERA
Get the best bets with Dimers Pro

Orioles vs. Diamondbacks Odds [4/9/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Orioles Diamondbacks
Moneyline +100 -115
Total o9 (-115) u9 (+100)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Orioles vs. Diamondbacks Picks and Best Bets

Our model's strongest edge in today's Orioles vs. Diamondbacks matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Orioles vs. Diamondbacks Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Diamondbacks and Orioles at Chase Field is scheduled to begin at 3:40PM ET.

Dimers.com's in-depth preview of Wednesday's Orioles vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Baltimore vs. Arizona picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Diamondbacks, with a 52% win probability, will likely beat the Orioles on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate probabilities for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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