Athletics vs. Astros Prediction and Odds - Sep 15, 2022

The Houston Astros square off with the Oakland Athletics in MLB action at Minute Maid Park on Thursday, beginning at 7:20PM ET.

The Astros will send Lance McCullers Jr. (3-1, 2.20 ERA) to the mound, while the Athletics will counter with James Kaprielian (3-9, 4.79 ERA).

Dimers' free betting picks for Athletics vs. Astros, as well as game predictions and best odds, are featured in this article.

Who will win Athletics vs. Astros?

Using state-of-the-art machine learning and data, Dimers.com has simulated Thursday's Athletics-Astros MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Astros a 73% chance of beating the Athletics.

More: Full Betting Guide for Athletics vs. Astros

Athletics vs. Astros Game Odds

• Run Line: Astros -1.5 (-145), Athletics +1.5 (+126)
• Moneyline: Astros -300, Athletics +260
• Total: Over/Under 8 (-105/-110)

Run Line, Moneyline and Over/Under

The Astros are listed as -1.5 favorites versus the Athletics, with -145 at Caesars Sportsbook the best odds currently available.

For the underdog Athletics (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +126.

BetMGM currently has the best moneyline odds for the Astros at -300, which means you can risk $300 to win $100, for a total payout of $400, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Athletics at +260, where you can bet $100 to profit $260, earning a total payout of $360, if they win.

The Over/Under for total runs scored sits at 8 with DraftKings Sportsbook, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out all of the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Astros (-1.5) are a 57% chance of covering the run line, while the Over/Under total of 8 runs is a 53% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Athletics vs. Astros

• Run Line: Athletics +1.5 @ +126 via FanDuel Sportsbook
• Moneyline: Athletics @ +260 via FanDuel Sportsbook
• Total: Over 8 @ -105 via DraftKings Sportsbook (53% probability)

Our best bets are based on detailed simulations and gambling intelligence to help you make better decisions with the legal sportsbooks in the United States.

Even though the Astros are more likely to cover the run line, our best bet of Athletics +1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

And while the Astros are more likely to win the game, according to DimersBOT, betting on the Athletics moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is one of the keys to achieving long-term profitability as a bettor.

Athletics vs. Astros Prediction

Click or tap on See Matchup to reveal more.

Dimers has full coverage of Thursday's Athletics-Astros matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for any changes to our betting analysis before Athletics vs. Astros on Thursday September 15, 2022.

Athletics vs. Astros 2022 Game Info

Thursday's matchup between the Astros and Athletics at Minute Maid Park is scheduled to start at 7:20PM ET.

• Who: Oakland Athletics vs. Houston Astros
• Date: Thursday September 15, 2022
• Time: 7:20PM ET / 4:20PM PT
• Venue: Minute Maid Park

Ready to join an online sportsbook and start betting on MLB now? We've listed the best available sign-up offers in every legal betting state.

What other MLB games are on today?

Now you've got the 411 on Athletics vs. Astros, get the latest betting predictions for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, plus our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.