Astros vs. Mariners Prediction and Odds - Jul 22, 2022

The Seattle Mariners and Houston Astros lock horns in MLB at T-Mobile Park on Friday, starting at 10:10PM ET.

Marco Gonzales (5-9, 3.50 ERA) will start on the mound for the Mariners, while the Astros are going with José Urquidy (8-4, 4.09 ERA).

Dimers' free betting picks for Astros vs. Mariners, plus game predictions and betting odds, are featured below.

Who will win Astros vs. Mariners?

Using state-of-the-art machine learning and data, Dimers.com has simulated Friday's Astros-Mariners MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Astros a 55% chance of getting the W against the Mariners.

More: Astros vs. Mariners Simulated 10,000 Times

Astros vs. Mariners Game Odds

• Run Line: Mariners +1.5 (-155), Astros -1.5 (+140)
• Moneyline: Mariners +110, Astros -120
• Total: Over/Under 8.5 (-105/-105)

Run Line, Moneyline and Over/Under

The Mariners are currently +1.5 underdogs against the Astros, with -155 at BetMGM the best odds currently available.

For the favored Astros (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +140.

FanDuel Sportsbook currently has the best moneyline odds for the Mariners at +110. That means you can bet $100 to profit $110, earning a total payout of $210, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Astros at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under for total runs scored sits at 8.5 with PointsBet, which currently has the best odds for the Over at -105, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 58% chance of covering the run line, while the Over/Under total of 8.5 runs is a 52% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Astros vs. Mariners

• Run Line: Astros -1.5 @ +140 via DraftKings Sportsbook (0.3% edge)
• Moneyline: Astros @ -120 via DraftKings Sportsbook (55% probability)
• Total: Over 8.5 @ -105 via PointsBet (52% probability)

Dimers' best bets are based on complex modeling and gambling intelligence to serve you the best possible plays 24/7/365.

Although the Mariners are more likely to cover the run line, our best bet of Astros -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Astros vs. Mariners Prediction

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Seattle, and click or tap on See Matchup for more.

Dimers has full betting coverage of Friday's Astros-Mariners matchup, including pregame predictions, top betting picks, and live updates.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis before Astros vs. Mariners on Friday July 22, 2022.

Get a Risk-Free Bet for Astros vs. Mariners

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Astros vs. Mariners 2022 Game Info

Friday's action between the Mariners and Astros at T-Mobile Park is scheduled to start at 10:10PM ET.

• Who: Seattle Mariners vs. Houston Astros
• Date: Friday July 22, 2022
• Time: 10:10PM ET / 7:10PM PT
• Venue: T-Mobile Park

Looking to join an online sportsbook and start betting on MLB? Check out the best sportsbook offers in your state.

What other MLB games are on today?

The Astros and Mariners aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for every single MLB game via our MLB Predictions section.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.