Astros vs. Guardians Prediction and Odds - Aug 4, 2022

The Cleveland Guardians take on the Houston Astros in MLB action at Progressive Field on Thursday, starting at 7:10PM ET.

Zach Plesac (2-9, 4.33 ERA) will be on the bump for the Guardians, pitting him against Justin Verlander (14-3, 1.82 ERA) for the Astros.

Dimers' top betting picks for Astros vs. Guardians, as well as game predictions and best odds, are featured below.

Who will win Astros vs. Guardians?

Based on high-tech computer power and data, Dimers.com has simulated Thursday's Astros-Guardians MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Astros a 60% chance of beating the Guardians.

More: Astros vs. Guardians Simulated 10,000 Times

Astros vs. Guardians Current Odds

• Run Line: Guardians +1.5 (+100), Astros -1.5 (-110)
• Moneyline: Guardians +158, Astros -175
• Total: Over/Under 8 (-106/-105)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs against the Astros, with +100 at Caesars Sportsbook the best odds currently available.

For the favored Astros (-1.5) to cover the run line, BetMGM has the best odds currently on offer at -110.

Caesars Sportsbook currently has the best moneyline odds for the Guardians at +158. That means you can bet $100 to profit $158, earning a total payout of $258, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Astros at -175, where you can risk $175 to win $100, for a total payout of $275, if they come out on top.

The Over/Under sits at 8 with FanDuel Sportsbook, which currently has the best odds for the Over at -106, while PointsBet currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 53% chance of covering the run line, while the Over/Under total of 8 runs is a 56% chance of going Over.

More: Best Bets for Every MLB Game

Best Bets for Astros vs. Guardians

• Run Line: Guardians +1.5 @ +100 via Caesars Sportsbook (53% probability)
• Moneyline: Guardians @ +158 via Caesars Sportsbook (1.3% edge)
• Total: Over 8 @ -106 via FanDuel Sportsbook (56% probability) 🔥

Every time you see a 🔥, you know you've found one of our best free picks today across all sports.

Our best bets are based on world-class modeling and wagering expertise to serve you the best possible plays every time.

While the Astros are more likely to win the game, according to DimersBOT, betting on the Guardians moneyline is the best option due to the 1.3% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published here at Dimers is crucial to achieving long-term profitability.

Astros vs. Guardians Prediction

Use our widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Cleveland, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Thursday's Astros-Guardians matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for any changes to our betting analysis before Astros vs. Guardians on Thursday August 4, 2022.

Best Betting Promo for Astros vs. Guardians

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Astros vs. Guardians 2022 Game Info

Thursday's matchup between the Guardians and Astros at Progressive Field is scheduled to begin at 7:10PM ET.

• Who: Cleveland Guardians vs. Houston Astros
• Date: Thursday August 4, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Progressive Field

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Want more MLB predictions like this?

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