Astros vs. Blue Jays Prediction and Odds - Apr 29, 2022

The Toronto Blue Jays square off with the Houston Astros in MLB action at Rogers Centre on Friday, starting at 7:07PM ET.

Yusei Kikuchi (0-1, 3.75 ERA) will start on the mound for the Blue Jays, up against José Urquidy (1-1, 5.52 ERA) for the Astros.

Dimers' free betting picks for Astros vs. Blue Jays, as well as game predictions and best odds, are featured below.

Who will win Astros vs. Blue Jays?

Using trusted machine learning and data, Dimers.com has simulated Friday's Astros-Blue Jays MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Blue Jays a 54% chance of defeating the Astros.

More: Astros vs. Blue Jays Simulated 10,000 Times

Astros vs. Blue Jays Odds

• Run Line: Blue Jays +1.5 (-190), Astros -1.5 (+184)
• Moneyline: Blue Jays -120, Astros +102
• Total: Over/Under 8 (-118/-104)

Run Line, Moneyline and Over/Under

The Blue Jays are +1.5 underdogs versus the Astros, with -190 at BetMGM the best odds currently available.

For the favored Astros (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +184.

BetMGM currently has the best moneyline odds for the Blue Jays at -120, which means you can risk $120 to win $100, for a total payout of $220, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Astros at +102, where you can bet $100 to profit $102, earning a total payout of $202, if they win.

The Over/Under is set at 8 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, as well as the best odds for the Under at -104.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Blue Jays (+1.5) are a 66% chance of covering the run line, while the Over/Under total of 8 runs is a 57% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Astros vs. Blue Jays

• Run Line: Blue Jays +1.5 @ -190 via BetMGM (66% probability)
• Moneyline: Blue Jays @ -120 via BetMGM (54% probability)
• Total: Over 8 @ -118 via FanDuel Sportsbook (57% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in your state.

Astros vs. Blue Jays Betting Guide

Use our interactive widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Toronto, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Friday's Astros-Blue Jays matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for the latest betting analysis before Astros vs. Blue Jays on Friday April 29, 2022.

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Astros vs. Blue Jays 2022 Game Info

When do the Blue Jays play the Astros?

• Date: Friday April 29, 2022
• Time: 7:07PM ET / 4:07PM PT
• Venue: Rogers Centre

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Want more MLB predictions like this?

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It's only a click away, so why not see for yourself?

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.