Arizona vs. Duke Prediction: Duke Predicted to Win NCAA Tournament Sweet Sixteen Matchup [3/27/2025]

Duke will face Arizona in March Madness Sweet Sixteen action at Prudential Center on Thursday, beginning at 9:55PM ET.

Based on updated simulations, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Duke as the most likely winner of today's game.

Check the latest March Madness player prop projections and 2025 NCAA Championship probabilities from our expert team.

"Using the latest data, our experts simulated Thursday's Arizona-Duke game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast Duke with a win probability of 81% and Arizona with 19%."

For expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Arizona vs. Duke predictions page.

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Arizona vs. Duke Prediction: Who Will Win and Advance to the Elite Eight?

Using innovative machine learning and data, we have simulated the result of Thursday's NCAA Tournament matchup between Arizona and Duke 10,000 times as part of our March Madness predictions coverage.

Our leading predictive model gives Duke an 81% chance of defeating Arizona. Our predicted final score has Duke winning 81-72.

According to our model, Duke (-9.5) has a 51% chance of covering the spread, while the over/under total of 154.5 points has a 52% chance of staying under.

Arizona vs. Duke March Madness Odds

We have sourced the best March Madness odds in America for this Sweet 16 game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boost your betting this month with the top March Madness betting sites and March Madness betting promos, sourced from top sportsbooks and DFS operators.

Arizona vs. Duke Picks and Best Bets

Our model's strongest edge in today's Arizona vs. Duke matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best March Madness picks and March Madness best bets for every game throughout the tournament.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Arizona vs. Duke Game-Day Updates and Essential Details

Thursday's college basketball game between Duke and Arizona at Prudential Center is scheduled to commence at 9:55PM ET.

• Who: Arizona vs. Duke
• Date: Thursday, March 27, 2025
• Time: 9:55PM ET/6:55PM PT
• Venue: Prudential Center
• March Madness Stage: Sweet 16

Dimers.com's in-depth preview of Thursday's Arizona vs. Duke matchup includes our prediction, picks and the latest betting odds.

Before making any Arizona vs. Duke picks, be sure to check out the latest March Madness predictions and betting advice from Dimers Pro.

Key March Madness Guides and Insights

• Learn about NCAA Championship history and the lowest-seeded team to ever win March Madness
• Get answers to legal questions, including which states you can legally bet on college sports and the minimum age required to place a bet on March Madness
• A breakdown of March Madness futures bets and popular prop bets for the NCAA tournament
• Explore strategy with guides on identifying value bets during the tournament and betting on individual player awards like Tournament MVP
• Understand the tournament format, including how many games are played in March Madness and how venue locations impact teams when playing at neutral sites

Conclusion

We predict Duke, with an 81% win probability, will likely beat Arizona on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Arizona vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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