Diamondbacks vs. Nationals Prediction: Arizona Predicted to Win Saturday's MLB Matchup [4/5/2025]

The Washington Nationals and Arizona dbacks will meet in MLB action at Nationals Park on Saturday, starting at 4:05PM ET.

The Nationals will send Mitchell Parker (1-0, 0.00 ERA) to the mound, up against Eduardo Rodriguez (0-0, 5.06 ERA) for the Diamondbacks.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Arizona-Washington game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Diamondbacks are more likely to win, while the Nationals have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Diamondbacks vs. Nationals predictions page.

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Diamondbacks vs. Diamondbacks Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB matchup between the Diamondbacks and Nationals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Diamondbacks a 53% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 59% chance of covering the run line, while the over/under total of 9.5 runs has a 58% chance of staying under.

Pre-Game Probabilities

Last Updated: 8:28PM, Apr 5

Moneyline

Over / Under

Run Line

D-Backs

Win %

53%

47%

-130

+115

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Nationals

D-Backs ARI

-130

Win %

53%

47%

See Matchup

Nationals WSH

+115

Eduardo Rodriguez 0-0, 5.06 ERA

Mitchell Parker 1-0, 0.00 ERA

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Diamondbacks vs. Nationals Odds [4/5/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Diamondbacks vs. Nationals Picks and Best Bets

Our model's strongest edge in today's Diamondbacks vs. Nationals matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Diamondbacks vs. Nationals Game-Day Updates and Essential Details

Saturday's MLB action between the Nationals and Diamondbacks at Nationals Park is scheduled to begin at 4:05PM ET.

• Who: Arizona Diamondbacks vs. Washington Nationals
• Date: Saturday, April 5, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Nationals Park

Dimers.com's in-depth preview of Saturday's Diamondbacks vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any Arizona vs. Washington picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Diamondbacks, with a 53% win probability, will likely beat the Nationals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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