Cardinals vs. 49ers Prediction: San Francisco Predicted to Win Following Latest Data Analysis for NFL Week 5 [2024]

The San Francisco 49ers and Arizona Cardinals are scheduled to meet in Week 5 of the NFL season at Levi's Stadium on Sunday, starting at 4:05PM ET.

Based on updated simulation results, Dimers' proven NFL model (see Dimers Pro for full access) predicts the 49ers as the most likely winner of the game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Cardinals-49ers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the 49ers with a win probability of 72%, while the Cardinals have 28%."

Cardinals vs. 49ers Game-Day Updates and Essential Details

The NFL Week 5 game between the 49ers and Cardinals at Levi's Stadium is scheduled to commence at 4:05PM ET.

• Who: Arizona Cardinals vs. San Francisco 49ers
• Date: Sunday, October 6, 2024
• Time: 4:05PM ET/1:05PM PT
• Venue: Levi's Stadium
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy 49ers and Cardinals gear at Fanatics
• Live Stream: Watch this game on FOX via Hulu or FuboTV

Dimers.com's full preview of this week's Cardinals vs. 49ers matchup includes our prediction, picks and the latest betting odds.

Before making any 49ers vs. Cardinals picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

READER EXCLUSIVE: Sign up with code 20FOOTBALL at checkout right now to receive 20% off your first month of Dimers Pro! This offer won't last forever.

Cardinals vs. 49ers Predictions

Using innovative machine learning and data, we have simulated the outcome of Sunday's NFL matchup between the Cardinals and 49ers 10,000 times as part of our NFL predictions coverage.

Our leading predictive model gives the 49ers a 72% chance of beating the Cardinals in Week 5 of the NFL season. Our predicted final score has the 49ers winning 28-21.

According to our model, the Cardinals (+7.5) have a 54% chance of covering the spread, while the 49.5-point over/under has a 51% chance of going over.

In addition to our Cardinals vs. 49ers predictions, we've also here's what else we've got for this week's action:

• The Best NFL Week 5 Odds
• NFL Picks Straight Up for Week 5
• Picks Against The Spread for NFL Week 5

Cardinals vs. 49ers Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	Cardinals	49ers
Spread	+7.5 (-115)	-7.5 (-105)
Moneyline	+290	-345
Total	o49.5 (-110)	u49.5 (-110)

All odds are correct at the time of publication and are subject to change.

Cardinals vs. 49ers Picks

Our model's strongest edge in the Cardinals vs. 49ers matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our picks, including this one, is available via Dimers Pro.

Cardinals vs. 49ers TD Scorers

Who will score an anytime touchdown in Cardinals vs. 49ers?

According to our model, San Francisco's Jordan Mason is most likely to score the first TD in Cardinals vs. 49ers.

Our projections give Mason a 15.1% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 60.6% chance of reaching the end zone at any point during the game.

First Touchdown Scorer Predictions

Arizona Cardinals

Player	First TD Probability
James Conner	10.1%
Marvin Harrison	7.7%
Trey McBride	6.1%

San Francisco 49ers

Player	First TD Probability
Jordan Mason	15.1%
Deebo Samuel	9.5%
George Kittle	8.8%

Anytime Touchdown Scorer Predictions

Arizona Cardinals

Player	Anytime TD Probability
James Conner	45.9%
Marvin Harrison	37.0%
Trey McBride	29.4%

San Francisco 49ers

Player	Anytime TD Probability
Jordan Mason	60.6%
Deebo Samuel	42.4%
George Kittle	41.0%

Cardinals vs 49ers Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Cardinals and 49ers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Cardinals-49ers page now to access every player prop projection.

Cardinals vs. 49ers Quarterbacks

Of the starting quarterbacks, the Cardinals' Kyler Murray is projected to throw for fewer yards than the 49ers' Brock Purdy.

Cardinals Rushing

James Conner, Kyler Murray and Trey Benson are projected to be the leading rushers for the Cardinals.

Player	Position
James Conner	RB
Kyler Murray	QB
Trey Benson	RB

49ers Rushing

Jordan Mason, Brock Purdy and Deebo Samuel are expected to lead the 49ers in rushing yards.

Player	Position
Jordan Mason	RB
Brock Purdy	QB
Deebo Samuel	WR

Cardinals Receiving

Marvin Harrison, Trey McBride, Michael Wilson, Greg Dortch and Elijah Higgins are projected to top the receiving yards for the Cardinals.

Player	Position
Marvin Harrison	WR
Trey McBride	TE
Michael Wilson	WR
Greg Dortch	WR
Elijah Higgins	TE

49ers Receiving

Brandon Aiyuk, George Kittle, Deebo Samuel, Jauan Jennings and Jordan Mason are projected to lead the 49ers in receiving yards.

Player	Position
Brandon Aiyuk	WR
George Kittle	TE
Deebo Samuel	WR
Jauan Jennings	WR
Jordan Mason	RB

NFL Fantasy and Betting Promos

Make the most of Dimers' Cardinals vs. 49ers predictions by exploring the two exciting offers below.

DraftKings Pick6

Sign up for DraftKings Pick6 today! Play $5 and get $50 in Pick6 Credits.

FanDuel Sportsbook

Get ready for NFL Week 5 by joining FanDuel Sportsbook! Bet $5 and get $200 in bonus bets.

Sports Betting Deal Available for Today

To make the most of Thursday's huge day of sports, headlined by the Cowboys-Giants clash, check out details on the latest Bet365 bonus code DIMERS that grants you the choice of two outstanding signup offers. Don't miss out!

Conclusion

We predict the 49ers, with a 72% win probability, will likely beat the Cardinals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. 49ers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Keep up with the latest NFL betting news and our data-driven NFL best bets and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most accurate predictions for the Super Bowl, AFC, NFC and each division.