Cardinals vs. 49ers Prediction: San Francisco Predicted to Win Following Latest Data Analysis for NFL Week 5 [2024]

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Written by Jason Bevilacqua
Arizona Cardinals-San Francisco 49ers Predictions and Game Preview.
Levi's Stadium sets the stage for the NFL matchup between the Arizona Cardinals and San Francisco 49ers this Sunday.

The San Francisco 49ers will square off with the Arizona Cardinals in NFL Week 5 action at Levi's Stadium on Sunday, commencing at 4:05PM ET.

Based on updated simulations, Dimers' advanced NFL model (see Dimers Pro for full access) predicts the 49ers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Cardinals-49ers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the 49ers with a win probability of 72%, while the Cardinals have 28%."

Cardinals vs. 49ers Game-Day Updates and Essential Details

The NFL Week 5 action between the 49ers and Cardinals at Levi's Stadium is scheduled to commence at 4:05PM ET.

Dimers.com's comprehensive preview of this week's Cardinals vs. 49ers matchup includes our prediction, picks and the latest betting odds.

Before making any 49ers vs. Cardinals picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

READER EXCLUSIVE: Sign up with code 20FOOTBALL at checkout right now to receive 20% off your first month of Dimers Pro! This offer won't last forever.

Cardinals vs. 49ers Predictions

Using innovative machine learning and data analysis, we have simulated the result of Sunday's NFL matchup between the Cardinals and 49ers 10,000 times as part of our NFL predictions coverage.

Our famous predictive model currently gives the 49ers a 72% chance of beating the Cardinals in Week 5 of the NFL season. Our predicted final score has the 49ers winning 27-20.

According to our model, the Cardinals (+7.5) have a 58% chance of covering the spread, while the 48.5-point over/under has an equal 50-50 chance of hitting.

 

In addition to our Cardinals vs. 49ers predictions, we've also prepared the following for today’s action:

Cardinals vs. 49ers Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type Cardinals 49ers
Spread +7.5 (-120) -7.5 (-102)
Moneyline +280 -325
Total o48.5 (-112) u48.5 (-105)

All odds are correct at the time of publication and are subject to change.

Cardinals vs. 49ers Picks

Our model's biggest edge in today's Cardinals vs. 49ers matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our picks, including this one, is available via Dimers Pro.

Cardinals vs. 49ers TD Scorers

Who will score an anytime touchdown in Cardinals vs. 49ers?

According to our model, San Francisco's Jordan Mason is most likely to score the first touchdown in Cardinals vs. 49ers.

Our projections give Mason a 15.5% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 60.8% chance of reaching the end zone at any point during the game.

First Touchdown Scorer Predictions

Arizona Cardinals

Player First TD Probability
James Conner 9.9%
Marvin Harrison 7.3%
Trey McBride 6.3%

San Francisco 49ers

Player First TD Probability
Jordan Mason 15.5%
Deebo Samuel 9.6%
Brandon Aiyuk 8.4%

Anytime Touchdown Scorer Predictions

Arizona Cardinals

Player Anytime TD Probability
James Conner 45.5%
Marvin Harrison 36.0%
Trey McBride 29.3%

San Francisco 49ers

Player Anytime TD Probability
Jordan Mason 60.8%
Deebo Samuel 43.4%
Brandon Aiyuk 39.6%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 5 touchdown scorer predictions

Cardinals vs 49ers Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Cardinals and 49ers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Cardinals-49ers page now to access every player prop projection.

Cardinals vs. 49ers Quarterbacks

Of the starting quarterbacks, the Cardinals' Kyler Murray is projected to throw for fewer yards than the 49ers' Brock Purdy.

Cardinals Rushing

James Conner, Kyler Murray and Trey Benson are projected to be the leading rushers for the Cardinals.

Player Position
James Conner RB
Kyler Murray QB
Trey Benson RB

49ers Rushing

Jordan Mason, Brock Purdy and Deebo Samuel are expected to lead the 49ers in rushing yards.

Player Position
Jordan Mason RB
Brock Purdy QB
Deebo Samuel WR

Cardinals Receiving

Marvin Harrison, Trey McBride, Michael Wilson, Greg Dortch and Elijah Higgins are projected to top the receiving yards for the Cardinals.

Player Position
Marvin Harrison WR
Trey McBride TE
Michael Wilson WR
Greg Dortch WR
Elijah Higgins TE

49ers Receiving

Brandon Aiyuk, George Kittle, Deebo Samuel, Jauan Jennings and Jordan Mason are projected to lead the 49ers in receiving yards.

Player Position
Brandon Aiyuk WR
George Kittle TE
Deebo Samuel WR
Jauan Jennings WR
Jordan Mason RB

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Conclusion

We predict the 49ers, with a 72% win probability, will likely beat the Cardinals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. 49ers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Keep up with the latest NFL betting news and our data-driven NFL best bets and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the latest predictions for the Super Bowl, AFC, NFC and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS and NFL, delivers game previews, best bets and props. He has contributed insightful articles at Dimers since 2020 as Head of Social and Community.

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