Angels vs. Guardians Prediction and Odds - Sep 14, 2022

The Cleveland Guardians and Los Angeles Angels clash in MLB at Progressive Field on Wednesday, starting at 1:10PM ET.

The Guardians will have Cal Quantrill (12-5, 3.50 ERA) start, up against Patrick Sandoval (5-9, 2.98 ERA) for the Angels.

Dimers' best betting picks for Angels vs. Guardians, as well as game predictions and best odds, are detailed below.

Who will win Angels vs. Guardians?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Angels-Guardians MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Guardians a 51% chance of defeating the Angels.

More: Angels vs. Guardians Simulated 10,000 Times

Angels vs. Guardians Odds

• Run Line: Guardians +1.5 (-192), Angels -1.5 (+175)
• Moneyline: Guardians -112, Angels -104
• Total: Over/Under 7.5 (+110/-128)

Run Line, Moneyline and Over/Under

The Guardians are listed as +1.5 underdogs against the Angels, with -192 at FanDuel Sportsbook the best odds currently available.

For the favored Angels (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +175.

In a sign of how close this game is expected to be, both the Guardians and Angels are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Guardians at -112, which means you can risk $112 to win $100, for a total payout of $212, if they get the W.

On the other hand, FanDuel Sportsbook also has the best moneyline odds for the Angels at -104, where you can risk $104 to win $100, for a total payout of $204, if they come out on top.

The Over/Under for total runs scored is set at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at +110, while FanDuel Sportsbook currently has the best odds for the Under at -128.

As always, check out all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 64% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Angels vs. Guardians

• Run Line: Angels -1.5 @ +175 via DraftKings Sportsbook
• Moneyline: Angels @ -104 via FanDuel Sportsbook
• Total: Over 7.5 @ +110 via Caesars Sportsbook (52% probability) 🔥

If you see a 🔥, you know it's one of our best bets today across all sports.

Dimers' best bets are based on detailed simulations and betting expertise to bring you the best possible plays every day of the year.

Although the Guardians are more likely to cover the run line, our best bet of Angels -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

And while the Guardians are more likely to win the game, according to DimersBOT, taking the Angels moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to being profitable in the long run.

Angels vs. Guardians Prediction

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Dimers has full coverage of Wednesday's Angels-Guardians matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this page for any changes to our betting insights ahead of Angels vs. Guardians on Wednesday September 14, 2022.

Angels vs. Guardians 2022 Game Info

Wednesday's action between the Guardians and Angels at Progressive Field is scheduled to commence at 1:10PM ET.

• Who: Los Angeles Angels vs. Cleveland Guardians
• Date: Wednesday September 14, 2022
• Time: 1:10PM ET / 10:10AM PT
• Venue: Progressive Field

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