Angels vs. Guardians Prediction and Odds - Sep 12, 2022

The Cleveland Guardians take on the Los Angeles Angels in MLB action at Progressive Field on Monday, starting at 6:10PM ET.

Konnor Pilkington (1-2, 3.99 ERA) will be on the bump for the Guardians, while the Angels are going with Reid Detmers (5-5, 3.67 ERA).

Dimers' best betting picks for Angels vs. Guardians, as well as game predictions and betting odds, are detailed below.

Who will win Angels vs. Guardians?

Based on cutting-edge machine learning and data, Dimers.com has simulated Monday's Angels-Guardians MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Guardians a 56% chance of getting the W against the Angels.

More: Free Betting Analysis for Angels vs. Guardians

Angels vs. Guardians Odds

• Run Line: Guardians +1.5 (-190), Angels -1.5 (+175)
• Moneyline: Guardians -115, Angels +100
• Total: Over/Under 7.5 (-125/+105)

Run Line, Moneyline and Over/Under

The Guardians are listed as +1.5 underdogs versus the Angels, with -190 at BetMGM the best odds currently available.

For the favored Angels (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +175.

BetMGM currently has the best moneyline odds for the Guardians at -115. That means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Angels at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under is set at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -125, as well as the best odds for the Under at +105.

As always, check out all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 55% chance of covering the run line, while the 7.5-run Over/Under is a 55% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Angels vs. Guardians

• Run Line: Angels -1.5 @ +175 via DraftKings Sportsbook (8.7% edge) 🔥
• Moneyline: Guardians @ -115 via BetMGM (56% probability)
• Total: Over 7.5 @ -125 via Caesars Sportsbook (55% probability)

When you see a 🔥, that means it's one of Dimers' best bets of the day across any sport.

Our best bets are based on world-class modeling and gambling intelligence to help you make more informed decisions with your state's legal sportsbooks.

Even though the Guardians are more likely to cover the run line, our best bet of Angels -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.

Angels vs. Guardians Prediction

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Dimers has full coverage of Monday's Angels-Guardians matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep an eye on this article for the latest betting insights before Angels vs. Guardians on Monday September 12, 2022.

Angels vs. Guardians 2022 Game Info

Monday's game between the Guardians and Angels at Progressive Field is scheduled to commence at 6:10PM ET.

• Who: Los Angeles Angels vs. Cleveland Guardians
• Date: Monday September 12, 2022
• Time: 6:10PM ET / 3:10PM PT
• Venue: Progressive Field

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