Air Force vs. Louisville CFB Predictions and Odds - Dec 28, 2021

Updated: Dec 21, 2023, 3:36AM | First published: Dec 8, 2021, 2:34AM

Written by Kevin Hansen, Senior Sports Analyst

Air Force vs. Louisville CFB Predictions and Odds - Dec 28, 2021

Louisville and Air Force lock horns in the 2021 First Responder Bowl at Gerald J. Ford Stadium on Tuesday, with kickoff at 3:15PM EST.

Dimers' top betting picks for Air Force vs. Louisville, plus game predictions and best odds, are featured in this article.

Who will win the 2021 First Responder Bowl?

Using cutting-edge machine learning and data, Dimers.com has simulated the 2021 First Responder Bowl 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives Louisville a 64% chance of winning against Air Force.

MORE: Full Betting Analysis for Air Force vs. Louisville

Point Spread, Moneyline and Over/Under

Louisville is the -1.5 favorite versus Air Force, with -105 at FanDuel Sportsbook the best odds available.

For the underdog Air Force (+1.5) to cover the spread, PointsBet has the best odds on offer at -115.

In a sign of how close this game is expected to be, both Louisville and Air Force are at minus-money betting odds on the moneyline.

DraftKings Sportsbook has the best moneyline odds for Louisville at -110, which means you can risk $110 to win $100, for a total payout of $210, if it gets the W.

On the other hand, PointsBet has the best moneyline odds for Air Force at -105, where you can risk $105 to win $100, for a total payout of $205, if it comes out on top.

The Over/Under for total points scored is set at 54.5 with DraftKings Sportsbook, which has the best odds for the Over at -105, while BetMGM has the best odds for the Under at -110.

As always, check out all the legal sportbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Louisville (-1.5) is a 63% chance of covering the spread, while the 54.5-point Over/Under is a 57% chance of going Under.

MORE: Predictions for Every College Football Matchup

Best Bets for Air Force vs. Louisville

Spread: Louisville -1.5 at -105 with FanDuel Sportsbook (63% probability) 🔥
Moneyline: Louisville Win at -110 with DraftKings Sportsbook (64% probability) 🔥
Over/Under: Under 54.5 at -110 with BetMGM (57% probability) 🔥

Every time you see a 🔥, you know it's one of Dimers' best bets of the day across all major pro and college sports.

First Responder Bowl Score Prediction

Dimers.com's predicted final score for Air Force vs. Louisville at Gerald J. Ford Stadium on Tuesday has Louisville winning 28-22.

Use our widget below to view the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's Air Force-Louisville matchup, including pre-game predictions, best betting picks, and live updates.

Don't forget, DimersBOT updates frequently, so keep an eye on this page for the latest betting analysis before Air Force vs. Louisville on Tuesday December 28, 2021.

Best Betting Promo for Air Force vs. Louisville

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Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Air Force vs. Louisville 2021 CFB Game Info

When does Louisville play Air Force in College Football?

Date: Tuesday December 28, 2021
Time: 3:15PM EST / 12:15PM PST
Venue: Gerald J. Ford Stadium

Looking to join an online sportsbook and start betting on College Football today? We've listed the best available welcome offers for every legal betting state.

NCAA Football Bowl Odds 2021-22

Bowl season is here, baby, and Air Force and Louisville aren't the only two CFB teams you can bet on today.

DimersBOT never stops and we've got picks and top bets for every single NCAA Football bowl matchup below.

Not only do we provide with you first-class CFB predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline this postseason.

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College Football Playoff National Championship

Written by

Kevin Hansen

Senior Sports Analyst

Kevin Hansen specializes in NFL, NBA, MLB, and NHL content, using data-driven insights for sports betting. He provides simple, actionable betting tips to help bettors find an edge and pick winners.