49ers vs. Panthers Week 5 Prediction and Odds - Oct 9, 2022

The Carolina Panthers take on the San Francisco 49ers in NFL Week 5 action at Bank of America Stadium on Sunday, starting at 4:05PM ET.

Dimers' top betting picks for 49ers vs. Panthers, as well as game predictions, betting odds and touchdown scorer probabilities, are featured in this article.

Today's San Francisco vs. Carolina betting analysis is sponsored by FanDuel Sportsbook, which has a great No Sweat First Bet promo for new users.

Who will win 49ers vs. Panthers?

Using advanced computer power and data, Dimers.com has simulated Sunday's 49ers-Panthers NFL matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the 49ers a 69% chance of getting the W against the Panthers in Week 5 of the NFL season.

More: 49ers vs. Panthers Simulated 10,000 Times

49ers vs. Panthers Current Odds

• Spread: Panthers +6 (-110), 49ers -6 (-105)
• Moneyline: Panthers +220, 49ers -235
• Total: Over/Under 39.5 (-107/-104)

Point Spread, Moneyline and Over/Under

The Panthers are currently +6 underdogs against the 49ers, with -110 at Caesars Sportsbook the best odds currently available.

For the favored 49ers (-6) to cover the spread, PointsBet has the best odds currently on offer at -105.

BetMGM currently has the best moneyline odds for the Panthers at +220. That means you can bet $100 to profit $220, earning a total payout of $320, if they win.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the 49ers at -235, where you can risk $235 to win $100, for a total payout of $335, if they come out on top.

The Over/Under for total points scored sits at 39.5 with PointsBet, which currently has the best odds for the Over at -107, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, check out the sportsbooks you can bet with in your state for the best NFL odds and lines.

According to DimersBOT, the Panthers (+6) are a 54% chance of covering the spread, while the Over/Under total of 39.5 points is a 51% chance of going Over.

More: Best Free Bet Tracker

Best Bets for 49ers vs. Panthers

• Spread: Panthers +6 @ -110 via Caesars Sportsbook (54% probability)
• Moneyline: Panthers @ +220 via BetMGM
• Total: Over 39.5 @ -107 via PointsBet (51% probability)

Dimers' best bets are based on world-class modeling and wagering expertise to help you make smarter decisions with the legal sportsbooks in the United States.

While the 49ers are more likely to win the game, according to DimersBOT, betting on the Panthers moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is one of the keys to achieving long-term profitability as a sports bettor.

49ers vs. Panthers Prediction

Dimers.com's predicted final score for San Francisco vs. Carolina at Bank of America Stadium in Week 5 has the 49ers prevailing 22-17.

Click or tap on See Matchup for more.

Dimers has full coverage of this week's 49ers-Panthers matchup in Week 5, including pregame predictions, free picks, and live win probabilities.

49ers vs. Panthers Player Props

Who will score an anytime touchdown in 49ers vs. Panthers? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the 49ers and Panthers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you discover the best prop picks for Sunday's game.

According to DimersBOT, Carolina's Christian McCaffrey is most likely to score the first TD in 49ers vs. Panthers.

DimersBOT gives McCaffrey a 14.6% chance of scoring the first TD at Bank of America Stadium, while the Panthers RB is a 53.2% chance of scoring an anytime touchdown.

Scroll down for the complete list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

San Francisco 49ers

• Deebo Samuel: 13.2% probability
• Jeff Wilson: 11.0% probability
• Brandon Aiyuk: 8.2% probability
• George Kittle: 6.3% probability
• Jimmy Garoppolo: 5.3% probability

Carolina Panthers

• Christian McCaffrey: 14.6% probability
• DJ Moore: 6.5% probability
• Robbie Anderson: 5.8% probability
• Ian Thomas: 4.3% probability
• Baker Mayfield: 3.4% probability

Anytime Touchdown Scorer Probabilities

San Francisco 49ers

• Deebo Samuel: 45.8% probability
• Jeff Wilson: 40.5% probability
• Brandon Aiyuk: 31.6% probability
• George Kittle: 25.6% probability
• Jimmy Garoppolo: 21.8% probability

Carolina Panthers

• Christian McCaffrey: 53.2% probability
• DJ Moore: 26.9% probability
• Robbie Anderson: 23.8% probability
• Ian Thomas: 19.0% probability
• Baker Mayfield: 14.5% probability

49ers-Panthers Projected Player Stats

Of the starting quarterbacks, the 49ers' Jimmy Garoppolo is projected for 252 passing yards. The Panthers' Baker Mayfield is expected to throw for 202 yards.

49ers Starting QB

• Jimmy Garoppolo: 252 projected yards

Panthers Starting QB

• Baker Mayfield: 202 projected yards

49ers Rushing

• Jeff Wilson: 69 projected yards
• Deebo Samuel: 24 projected yards
• Marlon Mack: 16 projected yards

Panthers Rushing

• Christian McCaffrey: 62 projected yards
• Baker Mayfield: 11 projected yards
• Chuba Hubbard: 11 projected yards

49ers Receiving

• Deebo Samuel: 56 projected yards
• George Kittle: 48 projected yards
• Brandon Aiyuk: 44 projected yards
• Jauan Jennings: 20 projected yards
• Kyle Juszczyk: 18 projected yards

Panthers Receiving

• Christian McCaffrey: 49 projected yards
• DJ Moore: 39 projected yards
• Shi Smith: 33 projected yards
• Robbie Anderson: 26 projected yards
• Ian Thomas: 18 projected yards

Remember, DimersBOT updates frequently, so keep checking this article for the latest betting insights before 49ers vs. Panthers on Sunday October 9, 2022.

49ers vs. Panthers 2022

The NFL Week 5 matchup between the Panthers and 49ers at Bank of America Stadium is scheduled to commence at 4:05PM ET.

• Who: San Francisco 49ers vs. Carolina Panthers
• Date: Sunday October 9, 2022
• Time: 4:05PM ET / 1:05PM PT
• Venue: Bank of America Stadium

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Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!