49ers vs. Jaguars Prediction, Week 10 Odds, NFL Player Props [2023]

The Jacksonville Jaguars and San Francisco 49ers will lock horns in Week 10 of the NFL season at EverBank Stadium on Sunday, with kickoff at 1:00PM ET.

Dimers' prediction for Sunday's 49ers vs. Jaguars game, plus the latest odds and our full game preview, are featured in this article.

This San Francisco vs. Jacksonville prediction is presented by Bet365, which has a Bet $5, Get $150 in Bonus Bets offer for new customers.

Who Will Win: 49ers vs. Jaguars

Based on advanced machine learning and data, Dimers.com has simulated the outcome of Sunday's 49ers-Jaguars NFL matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the 49ers a 59% chance of beating the Jaguars in Week 10 of the NFL season.

More: 49ers vs. Jaguars Simulated 10K Times

49ers vs. Jaguars Odds

We have researched the best betting odds in America for this game, which are listed here:

• Spread: Jaguars +3 (+100), 49ers -3 (-110)
• Moneyline: Jaguars +145, 49ers -168
• Total: Over/Under 44.5 (-108/-108)

Odds are correct at the time of publication and subject to change.

The Jaguars are listed as +3 underdogs versus the 49ers, with +100 at BetMGM the best odds currently available.

For the favored 49ers (-3) to cover the spread, PointsBet has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for the Jaguars at +145, which means you can bet $100 to profit $145, earning a total payout of $245, if they win.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the 49ers at -168, where you can risk $168 to win $100, for a total payout of $268, if they come out on top.

The Over/Under is set at 44.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -108, while FanDuel Sportsbook currently has the best odds for the Under at -108.

As always, make sure you check all of the online sportsbooks that are available in your state for the best NFL odds and lines.

According to DimersBOT, the Jaguars (+3) have a 58% chance of covering the spread, while the Over/Under total of 44.5 points has an equal 50-50 chance of hitting.

More: Best Prop Bets Today

Best Bets: 49ers vs. Jaguars

• Spread: Jaguars +3 @ +100 via BetMGM (58% probability) 🔥
• Moneyline: Jaguars @ +145 via BetMGM (0.6% edge)
• Total: Over 44.5 @ -108 via DraftKings Sportsbook (50% probability)

When you see a 🔥, you know you've found one of Dimers' best free picks today across any sport.

Dimers' best bets are based on world-class modeling and gambling intelligence to bring you the best possible plays 24/7/365.

While the 49ers are more likely to win the game, according to DimersBOT, taking the Jaguars moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published on Dimers is crucial to being profitable in the long run.

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49ers vs. Jaguars Prediction

Dimers.com's predicted final score for San Francisco vs. Jacksonville at EverBank Stadium in Week 10 has the 49ers winning 23-21.

Click or tap on See Matchup to find out more.

Dimers has full coverage of this week's 49ers vs. Jaguars game in Week 10, including pregame predictions, free NFL picks, and live win probabilities.

49ers vs. Jaguars Player Props

Who will score the first touchdown in 49ers vs. Jaguars? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the 49ers and Jaguars, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop bets for Sunday's game.

According to DimersBOT, San Francisco's Christian McCaffrey is most likely to score the first TD in 49ers vs. Jaguars.

DimersBOT gives McCaffrey an 18.3% chance of getting in for six first at EverBank Stadium, while the 49ers RB is a 64.2% chance of scoring an anytime touchdown.

Scroll down for our complete list of first and anytime TD scorer probabilities, which provide a great avenue for you to use this DraftKings Sportsbook offer, which unlocks $200 in bonus bets from a $5 bet on any of the below players.

First Touchdown Scorer Probabilities

San Francisco 49ers

• Christian McCaffrey: 18.3% probability
• Brandon Aiyuk: 8.7% probability
• Deebo Samuel: 8.5% probability
• George Kittle: 7.6% probability
• Ray-Ray McCloud: 2.6% probability

Jacksonville Jaguars

• Travis Etienne: 12.0% probability
• Calvin Ridley: 7.2% probability
• Christian Kirk: 6.9% probability
• Evan Engram: 6.5% probability
• Trevor Lawrence: 5.5% probability

Anytime Touchdown Scorer Probabilities

San Francisco 49ers

• Christian McCaffrey: 64.2% probability
• Brandon Aiyuk: 37.1% probability
• Deebo Samuel: 36.6% probability
• George Kittle: 33.1% probability
• Elijah Mitchell: 12.2% probability

Jacksonville Jaguars

• Travis Etienne: 48.4% probability
• Calvin Ridley: 31.9% probability
• Christian Kirk: 30.6% probability
• Evan Engram: 29.3% probability
• Trevor Lawrence: 25.5% probability

49ers-Jaguars Projected Player Stats

Of the starting quarterbacks, the 49ers' Brock Purdy is projected for 242 passing yards. The Jaguars' Trevor Lawrence is expected to throw for 241 yards.

49ers Starting QB

• Brock Purdy: 242 projected yards

Jaguars Starting QB

• Trevor Lawrence: 241 projected yards

49ers Rushing

• Christian McCaffrey: 81 projected yards
• Brock Purdy: 12 projected yards
• Deebo Samuel: 12 projected yards

Jaguars Rushing

• Travis Etienne: 72 projected yards
• Trevor Lawrence: 18 projected yards
• Tank Bigsby: 11 projected yards

49ers Receiving

• Brandon Aiyuk: 65 projected yards
• Deebo Samuel: 52 projected yards
• George Kittle: 46 projected yards
• Christian McCaffrey: 31 projected yards
• Jauan Jennings: 17 projected yards

Jaguars Receiving

• Evan Engram: 61 projected yards
• Christian Kirk: 55 projected yards
• Calvin Ridley: 55 projected yards
• Travis Etienne: 26 projected yards
• Jamal Agnew: 16 projected yards

Remember, DimersBOT updates regularly, so check this page for any changes to our betting analysis before 49ers vs. Jaguars on Sunday November 12, 2023.

49ers vs. Jaguars Preview

The NFL Week 10 action between the Jaguars and 49ers at EverBank Stadium is scheduled to start at 1:00PM ET.

• Who: San Francisco 49ers vs. Jacksonville Jaguars
• Date: Sunday November 12, 2023
• Time: 1:00PM ET / 10:00AM PT
• Venue: EverBank Stadium

How to Bet on 49ers vs. Jaguars

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These fees help us keep Dimers free for sports fans like you. So, if you like what you see, support us by joining one of our featured sports betting partners, including DraftKings Sportsbook, where you get $200 in bonus bets for signing up and bettting $5 on San Francisco vs. Jacksonville.

Conclusion

This comprehensive NFL preview centers around our 49ers vs. Jaguars prediction and Week 10 odds.

Dimers' predictions are made thanks to 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these 49ers vs. Jaguars picks can help you make informed decisions, it's vital that you gamble responsibly and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What NFL Games Are on Today?

The 49ers and Jaguars aren't the only two NFL teams you can bet on. DimersBOT never stops and we've got picks and best bets for each and every NFL matchup via our NFL predictions. Not only do we provide with you quality predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Hell yeah it does!

In addition to our leading NFL predictions, we also feature the best NFL prop bets today, projecting passing yards, touchdowns, and more against the top odds available every single day of the NFL season.