Yankees vs. Guardians Prediction, Picks and Odds

Our detailed prediction and analysis for the Yankees vs. Guardians MLB game on April 22, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Yankees
2
3
Apr 22, 10:10PM Progressive Field
Guardians
Apr 22, 10:10PM Progressive Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
Yankees
1 0 0 0 0 1 0 0 0 2 6 1
Guardians
0 0 0 0 0 3 0 0 X 3 6 1
Live Probabilities
Moneyline
Over / Under
Run Line
Yankees NYY
Win %
0%
100%
Guardians CLE
Win Probability
Created with Highcharts 10.3.3Inning% ProbabilityYankeesGuardiansE1E2E3E4E5E6E7E8F0255075100
Created with Highcharts 10.3.3Inning% ProbabilityYankees -1.5Guardians +1.5E1E2E3E4E5E6E7E8F0255075100
Created with Highcharts 10.3.3Inning% ProbabilityOver 8.5Under 8.5E1E2E3E4E5E6E7E8F0255075100
Last At Bat
Outs
Oswaldo Cabrera grounds out to second base, Gabriel Arias to Carlos Santana.
Quick Box Score
Hitting
Pitching
Yankees Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 B. Rice DH41111010.251.250
2 A. Judge RF414000012.250
3 C. Bellinger CF400000200.000
4 P. Goldschmidt 1B30100110.3330.833
5 J. Chisholm 2B100102000.500
6 A. Volpe SS300001100.250
7 J. Domínguez LF400000200.000
8 A. Wells C100000000.000
9 O. Cabrera 3B400000100.000
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF41200000.51.000
2 G. Arias 2B100000000.000
3 J. Ramírez 3B400000100.000
4 K. Manzardo DH41110010.250.750
5 C. Santana 1B400000200.000
6 B. Naylor C300001000.250
7 A. Martínez CF30110000.3330.666
8 D. Schneemann RF20100110.51.167
9 B. Rocchio SS300000000.000

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Yankees vs. Guardians: Detailed Breakdown

Matchup Overview

  • Teams: Yankees vs. Guardians
  • Date: Tuesday, April 22, 2025
  • Time: 6:10 PM ET
  • Venue: Progressive Field

Current Betting Odds

  • Spread: Yankees favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: Yankees +102, Guardians -115

Dimers' Win Probabilities

  • Yankees: 51%
  • Guardians: 49%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Yankees a win probability of 51%, while the Guardians have a win probability of 49%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Yankees are more likely to beat the Guardians in the MLB game at Progressive Field on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Yankees vs. Guardians predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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