Yankees vs. Guardians Prediction, Picks and Odds

Our detailed prediction and analysis for the Yankees vs. Guardians MLB game on April 21, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Yankees
4
6
Apr 21, 10:10PM Progressive Field
Guardians
Apr 21, 10:10PM Progressive Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
1 2 3 4 5 6 7 8 9 RHE
Yankees
0 0 0 0 0 0 2 2 0 4 10 0
Guardians
0 0 4 1 0 1 0 0 X 6 10 1
Live Probabilities
Moneyline
Over / Under
Run Line
Yankees NYY
Win %
0%
100%
Guardians CLE
Win Probability
Created with Highcharts 10.3.3Inning% ProbabilityYankeesGuardiansE1E2E3E4E5E6E7E8F0255075100
Created with Highcharts 10.3.3Inning% ProbabilityYankees -1.5Guardians +1.5E1E2E3E4E5E6E7E8F0255075100
Created with Highcharts 10.3.3Inning% ProbabilityOver 8.5Under 8.5E1E2E3E4E5E6E7E8F0255075100
Last At Bat
Outs
Aaron Judge strikes out swinging.
Quick Box Score
Hitting
Pitching
Yankees Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 A. Wells C500000100.000
2 A. Judge DH40100120.250.900
3 C. Bellinger CF40100000.250.500
4 P. Goldschmidt 1B31200110.6671.417
5 J. Chisholm 2B41121020.251.250
6 A. Volpe SS31100100.3330.833
7 J. Domínguez LF41121030.251.250
8 B. Rice PH100000000.000
9 O. Cabrera 3B40200010.51.000
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan LF42200100.51.350
2 J. Noel RF100000000.000
3 J. Ramírez 3B51241000.41.400
4 K. Manzardo DH31111110.3331.833
5 C. Santana 1B400000100.000
6 G. Arias SS40100020.250.500
7 A. Martínez CF41200000.51.250
8 B. Naylor C400000100.000
9 D. Schneemann 2B000000000.000

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Yankees vs. Guardians: Detailed Breakdown

Matchup Overview

  • Teams: Yankees vs. Guardians
  • Date: Monday, April 21, 2025
  • Time: 6:10 PM ET
  • Venue: Progressive Field

Current Betting Odds

  • Spread: Yankees favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: Yankees -124, Guardians +110

Dimers' Win Probabilities

  • Yankees: 49%
  • Guardians: 51%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Yankees a win probability of 49%, while the Guardians have a win probability of 51%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Guardians are more likely to beat the Yankees in the MLB game at Progressive Field on Monday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Yankees vs. Guardians predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.

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