Free MLB Picks Today: Friday's Best Bets Include Pirates vs. Dodgers Play [4/25/2025]

MLB betting is back for another attractive slate on 4/25, and we're here to serve up our top picks for Friday's baseball action.

Today's MLB best bets come from a range of matchups, including the Pirates vs. Dodgers game at 10:10PM ET, with this article updated throughout the day to highlight the most attractive upcoming games.

Led by a standout run line play with an edge of 3.8%, these picks are powered by data-driven simulations and machine learning.

For unlimited access to everything Dimers has to offer on Friday, April 25, 2025—including our complete set of MLB picks and best bets—check out Dimers Pro.

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List of MLB Best Bets Tonight [4/25, Updated: 10:01PM ET]

After digging deep into the numbers and conducting thousands of simulations, our independent predictive analytics model has identified the best baseball bets for Friday, April 25, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro users.

Pirates +1.5 (-122)

• Edge: 3.8%
• Probability: 58.8%
• Matchup: Pirates vs. Dodgers (10:10PM ET, Friday)

Our model has pinpointed the next MLB betting opportunity tonight, which comes in the Pirates vs. Dodgers matchup. We recommend a run line bet on Pirates +1.5 at -122 odds, offering an edge of 3.8%.

Pirates +1.5 vs. Dodgers

-122

Bet $25
Payout $45.50Bet $25, Payout $45.50

Pirates ML (+185)

• Edge: 2.0%
• Probability: 37.1%
• Matchup: Pirates vs. Dodgers (10:10PM ET, Friday)

Our model has found another great MLB bet for Friday's baseball action, again in the game between the Pirates and Dodgers. We suggest placing a wager on Pirates ML at +185 odds, with our analysis showing a compelling 2.0% edge.

Pirates ML vs. Dodgers

+185

Bet $25
Payout $71.25Bet $25, Payout $71.25

MORE: MLB Props

MLB Best Bets: Friday, 4/25/2025

As of 10:01PM ET, here are the next two MLB bets recommended by our model:

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you instant access to today's best bets across all sports, powered by our advanced model.

Among Friday's MLB picks is a +195 moneyline play with an edge of 2.1%.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for April 25, 2025.

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List of Upcoming MLB Games to Bet On [4/25/2025]

• White Sox vs. Athletics (10:05PM ET, Friday)
• Pirates vs. Dodgers (10:10PM ET, Friday)
• Rangers vs. Giants (10:15PM ET, Friday)
• Blue Jays vs. Yankees (1:05PM ET, Saturday)
• Angels vs. Twins (2:10PM ET, Saturday)
• Brewers vs. Cardinals (2:15PM ET, Saturday)
• Reds vs. Rockies (3:10PM ET, Saturday)
• Phillies vs. Cubs (4:05PM ET, Saturday)
• White Sox vs. Athletics (4:05PM ET, Saturday)
• Mets vs. Nationals (4:05PM ET, Saturday)
• Rangers vs. Giants (4:05PM ET, Saturday)
• Astros vs. Royals (7:10PM ET, Saturday)
• Braves vs. D-Backs (8:10PM ET, Saturday)
• Rays vs. Padres (8:40PM ET, Saturday)
• Pirates vs. Dodgers (9:10PM ET, Saturday)
• Marlins vs. Mariners (9:40PM ET, Saturday)

More About MLB

This article is part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.