Twins vs. Guardians Prediction: Tight Battle Projected in Updated Analysis for Monday's MLB Game [9/16/2024]

MLB action continues on Monday at 6:40PM ET as the Minnesota Twins take on the Cleveland Guardians at Progressive Field.

Matthew Boyd (2-1, 2.18 ERA) will be on the bump for the Guardians, pitting him against Pablo López (15-8, 3.88 ERA) for the Twins.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Guardians as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Twins-Guardians game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Guardians are likely to win, with a probability of 53%, compared to the Twins' 47%."

Twins vs. Guardians Game-Day Updates and Essential Details

Monday's MLB matchup between the Guardians and Twins at Progressive Field is scheduled to commence at 6:40PM ET.

• Who: Minnesota Twins vs. Cleveland Guardians
• Date: Monday, September 16, 2024
• Time: 6:40PM ET/3:40PM PT
• Venue: Progressive Field
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Guardians and Twins gear at Fanatics
• Live Stream: Watch the game on FuboTV

Dimers.com's in-depth preview of Monday's Twins vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Guardians vs. Twins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

READER EXCLUSIVE: Sign up with code 20BASEBALL at checkout right now to receive 20% off your first month of Dimers Pro! This offer won't last forever.

Twins vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Monday's MLB game between the Twins and Guardians 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Guardians a 53% chance of beating the Twins.

According to our model, the Guardians (+1.5) have a 66% chance of covering the run line, while the 7.5-run over/under has a 54% chance of going over.

Twins vs. Guardians Odds [9/16/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Twins	Guardians
Run Line	-1.5 (+142)	+1.5 (-162)
Moneyline	-118	+105
Total	o7.5 (+102)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

Twins vs. Guardians Picks

Our model's strongest edge in today's Twins vs. Guardians matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks for every game throughout the season.

Full access to our picks, including this one, is available via Dimers Pro.

Calling Our Shot: Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Conclusion

We predict the Guardians, with a 53% win probability, will likely beat the Twins on Monday.

AI and automation have enhanced this article to quickly deliver accurate Twins vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay updated with the latest MLB news and our data-led MLB best bets and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate projections for the World Series, American League, National League and each division.