Buffalo Bills vs. Indianapolis Colts Early Predictions for NFL Week 10: Odds, Picks and Preview [2024]

The Indianapolis Colts and Buffalo Bills will meet in Week 10 of the NFL season at Lucas Oil Stadium on Sunday, November 10, 2024, with kickoff set for 1:00PM ET.

Early simulations from Dimers' trusted NFL model (see Dimers Pro for full access) project the Bills as the most likely winner of this game.

Bills vs. Colts Week 10 Details

The NFL Week 10 game between the Colts and Bills at Lucas Oil Stadium is scheduled for November 10, 2024.

• Who: Buffalo Bills vs. Indianapolis Colts
• Date: Sunday, November 10, 2024
• Time: 1:00PM ET/10:00AM PT
• Venue: Lucas Oil Stadium

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Bills vs. Colts Opening Odds

We've researched the best betting odds in America for this Week 10 game, detailed below:

• Spread: Bills -2 (-110), Colts +2 (-110)
• Moneyline: Bills -130, Colts +110
• Total: Over/Under 46.5 (-110/-110)

Buffalo vs. Indianapolis Early Predictions

Leveraging powerful machine learning and analysis, we have simulated the Bills vs. Colts game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight Up Win Probabilities: Bills 57%, Colts 43%
• Predicted Final Score: Bills 23-21 Colts
• Spread: Bills (-2) 50%, Colts (+2) 50%
• Total Points (46.5): Over 47%, Under 53%

As of November 3, 2024, these Bills-Colts predictions reflect the latest data and insights available.

Conclusion

We predict the Bills, with a 57% win probability, will likely beat the Colts in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Bills vs. Colts game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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