Buffalo Bills vs. Detroit Lions Early Predictions for NFL Week 15: Odds, Picks and Preview [2024]

The Detroit Lions and Buffalo Bills will lock horns in Week 15 of the NFL season at Ford Field on Sunday, December 15, 2024, starting at 4:25PM ET.

Early simulation results from Dimers' proven NFL model project the Lions as the most likely winner of this showdown.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Bills vs. Lions predictions page.

Bills vs. Lions Week 15 Details

The NFL Week 15 action between the Lions and Bills at Ford Field is scheduled for December 15, 2024.

• Who: Buffalo Bills vs. Detroit Lions
• Date: Sunday, December 15, 2024
• Time: 4:25PM ET/1:25PM PT
• Venue: Ford Field

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Bills vs. Lions Opening Odds

We've researched the best betting odds in America for this Week 15 game, which are listed here:

• Spread: Bills +2 (-110), Lions -2 (-110)
• Moneyline: Bills +110, Lions -130
• Total: Over/Under 50.5 (-110/-110)

Buffalo vs. Detroit Early Predictions

Leveraging trusted machine learning and analysis, we have simulated the Bills vs. Lions game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight Up Win Probabilities: Bills 43%, Lions 57%
• Predicted Final Score: Bills 23-25 Lions
• Spread: Bills (+2) 50%, Lions (-2) 50%
• Total Points (50.5): Over 47%, Under 53%

As of December 8, 2024, these Bills-Lions predictions reflect the latest data and insights available.

Conclusion

We predict the Lions, with a 57% win probability, will likely beat the Bills in Week 15 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Bills vs. Lions game, with human oversight maintaining high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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